Results 201 to 210 of about 52,783 (282)

Innovative In Vivo Approaches to Bone Regeneration: Combining Chitosan‐Xanthan Gum Membranes, Electrical Stimulation, and Laser Therapy

open access: yesJournal of Biomedical Materials Research Part A, Volume 114, Issue 9, September 2026.
ABSTRACT Critical bone defects present significant clinical challenges due to their debilitating nature and associated costs. Tissue engineering offers a promising solution, employing biomaterials like porous chitosan (CH) and xanthan gum (XG) membranes as scaffolds for tissue regeneration.
Julia Eduarda Schneider Gregório   +7 more
wiley   +1 more source

miR‐138‐5p Inhibits Aortic Valve Interstitial by Targeting SLC39A14 and Activating Nrf2 Signaling

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Nrf2 Pathway Inhibition Attenuates miR‐138‐5p's Anti‐Calcification Effects in OM‐Induced hAVICs. A. ALP staining for ALP activity assessment in NC‐mimic, miR‐mimic, and miR‐mimic + ML385 groups. B. Alizarin Red staining for osteogenesis and calcium nIn osteogenic medium‐induced human aortic valve interstitial cells (hAVICs), miR‐138‐5p targets SLC39A14
Fei Yan   +9 more
wiley   +1 more source

Calpeptin Reduces Extracellular Vesicle Secretion and Induces Anti‐Inflammatory Effects but Upregulates HO‐1 and Alters Adiponectin Levels in Human Adipocytes

open access: yesJournal of Extracellular Biology, Volume 5, Issue 9, September 2026.
ABSTRACT Recent studies have shown that adipose tissue (AT) secretes elevated levels of extracellular vesicles (EVs) in obesity, and these EVs play roles in metabolic diseases. The inhibition of calpains has anti‐inflammatory and anti‐fibrotic effects on AT in mice and reduces EV secretion in some cell types in vitro.
Johanna Matilainen   +18 more
wiley   +1 more source

The Health Benefits of Exercise: Molecular and Cellular Mechanisms

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Our synthesis integrates evidence on exercise‐induced regulatory mechanisms across multiple systems (musculoskeletal, cardiovascular, nervous, metabolic and immune), cross‐system, and aging. We also discusses adaptive regulation of exercise in extreme environments, along with the prospects and challenges of multiomics and AI‐driven precision exercise ...
Peifeng Ying   +12 more
wiley   +1 more source

Tissue‐Resident Macrophage in Inflammation and Cancer

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Opposing macrophage functions in inflammation and cancer converge on shared mechanistic nodes, informing cross‐disease therapeutic strategies. ABSTRACT Tissue‐resident macrophages (TRMs) are long‐lived immune cells strategically distributed across organs, where their functional plasticity enables both homeostatic maintenance and pathological ...
Siyuan Huang   +13 more
wiley   +1 more source

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