Results 201 to 210 of about 75,213 (253)

PAX3 mutant mesoangioblasts are defective in myogenic differentiation [PDF]

, 2005
Sirabella, Dario
core  

Leveraging extracellular vesicle biology for novel tests and therapeutics for kidney fibrosis

Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.
Extracellular vesicles (EVs) are bilipid membrane‐encased nanoparticles that play critical roles as cell‐to‐cell messengers and waste management mechanisms. EVs cargos can be leveraged as biomarkers to develop minimally invasive tests for kidney fibrosis and guide personalised mechanism‐driven care.
Chin‐Ya Sophie Chiang, Andrew J. Kassianos, Helen Grania Healy, Monica Suet Ying Ng   +3 more
wiley   +1 more source

Circulating Molecular Drivers of Bone Remodeling in Pancreatitis. [PDF]

Clin Transl Gastroenterol
Hill RL, Yadav D, Hart PA, Whitcomb DC, McQuerry KJ, Karnik KN, Stello KM, Conwell DL, Rao M.   +8 more
europepmc   +1 more source

ZFP36L1 promotes non‐small cell lung cancer progression under hypoxia by modulating CXCL9:SPP1 polarity: A single‐cell transcriptomic study

Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.
1. Under hypoxia, downregulating the CXCL9:SPP1 ratio in macrophages promoted malignant progression of non‐small cell lung cancer (NSCLC). 2. Transcriptional factor ZFP36L1 modulated the CXCL9:SPP1 macrophage polarity. 3. ZFP36L1‐driven SPP1+ macrophages could accelerate NSCLC progression by binding to CD44 on the tumour cell surface.
Lijie Wang, Biao Chen, Jinxian He, Chengbin Lin, Weiyu Shen, Wang Lv, Luming Wang, Jian Hu   +7 more
wiley   +1 more source

Amino-Modified Mesoporous Bioactive Glass Adsorbed with Osteopontin Enhances Osteogenic Differentiation and Matrix Mineralization via the Erk1/2 Signaling Pathway. [PDF]

J Funct Biomater
Yang Y, Lin K, Zhou Z, Liu L, Liu L, Liu H, Mao H, Wang X.   +7 more
europepmc   +1 more source

Novel insights into extracellular vesicles: An update on biomolecules, immunomodulation and clinical strategies in skin melanoma

Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.
Extracellular vesicles mediate melanoma progression by transferring biomolecules (proteins, nucleic acids) that reshape the tumour microenvironment, promote immune evasion and drive metastasis. They also serve as diagnostic biomarkers and engineered therapeutic carriers for targeted therapy.
Junshu Li, Wencheng Zhou, Ying Cen, Yong Qing   +3 more
wiley   +1 more source

Optimizing graphene-enhanced polycaprolactone scaffolds for bone tissue engineering. [PDF]

J Oral Biol Craniofac Res
Anitasari S, Tandirogang N, Irawiraman H, Budi HS, Shen YK, Alus LN, Nuraini P.   +6 more
europepmc   +1 more source

Macrophage Cluster of Differentiation 163 promotes post‐infarction cardiac repair and preserves left ventricular function via osteopontin

Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.
• Circulating soluble CD163 is elevated in ischaemic cardiomyopathy and correlates with systolic dysfunction severity and ventricular dilation. • Macrophage CD163 protects against post‐infarction systolic dysfunction and left ventricular dilation in mice. • Loss of CD163 decreases macrophage osteopontin expression.
Jingyu Chen, Linjian Chen, Wei Huang, Gang Wang, Lin Wang, Wanchun Mei, Wei Ni, Yang Liu, Licheng Ding, Xiaofeng Ge, Zhaokai Li, Jing Yu, Shufen Huang, Jiayi Lin, Yifan Chen, Binni Cai, Peng Zhang, Cuilian Dai, Binbin Liu   +18 more
wiley   +1 more source

Osteogenic Differentiation Triggered by Intracellular Magnetoelectric Stimulation of Core-Shell Nanotransducers under Remotely Applied Magnetic Fields. [PDF]

ACS Nano
Mendes MC, Martins EAG, Chernozem RV, Chernozem PV, Custódio CC, Surmenev RA, Kholkin AL, Silva AS, Mano JF.   +8 more
europepmc   +1 more source