The pro-fibrogenic role of SPP1<sup>+</sup> macrophages in medical implant fibrosis: mechanisms and therapeutic opportunities. [PDF]
Yu M, Fu J.
europepmc +1 more source
In this study, we investigate the potential of urinary secreted phosphoprotein 1 (SPP1) levels as a noninvasive diagnostic biomarker for oesophageal squamous cell carcinoma (ESCC). Our study suggests that urinary SPP1 may serve as a novel biomarker for the detection of ESCC. Abstract Background Urinary proteins could be useful as noninvasive biomarkers
Bingrong Guo +5 more
wiley +1 more source
Exercise as a Biological Driver of Skeletal Muscle Regeneration and Repair: Implications for Regenerative Rehabilitation. [PDF]
Rando TA.
europepmc +1 more source
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam +4 more
wiley +1 more source
Relationship between SPP1 (Osteopontin) and extracellular matrix dynamics: a comprehensive review. [PDF]
Liu Y, Yan X, Fan R.
europepmc +1 more source
Biomaterial Physical Cues as Gene Regulators for Cellular Agriculture
This review elucidates how biomaterial physical cues—ranging from matrix stiffness to remote electromagnetic fields—serve as extrinsic regulators of gene expression in cellular agriculture. By identifying central mechanotransduction pathways that bridge physical inputs to genetic remodeling, the authors propose the “Material Genome” concept: a ...
Jianuo Liu, Ye Liu
wiley +1 more source
Plasma levels of thrombin-cleaved osteopontin as a surrogate biomarker of subsequent chronic shunt-dependent hydrocephalus development following aneurysmal subarachnoid hemorrhage. [PDF]
Aoki K +6 more
europepmc +1 more source
Insight to Neglected Biomarkers in COVID-19: A Comprehensive Narrative Review". [PDF]
Jalilian S, Bastani MN, Afsharzadeh F.
europepmc +1 more source
Vascular Calcification: Mechanisms, Models, and Therapies
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu +5 more
wiley +1 more source
Investigation of Osteopontin (OPN) Expression in Dromedary Camel (<i>Camelus dromedarius</i>) in the First Trimester of Pregnancy. [PDF]
Alrashaid FA +3 more
europepmc +1 more source

