Results 221 to 230 of about 75,213 (253)

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

MedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi, Shahin Ramazi, Mona Darvazi, Sepideh Yoosefi, Melika Abbasi, Shirin Farsad   +5 more
wiley   +1 more source

Multimodal analysis of biomineralization within a collagen scaffolding in a rat calvarial defect model by using decalcified and undecalcified specimens. [PDF]

J Mater Sci Mater Med
Shimada N, Hirata A, Yamada S, Ishizuka TA, Inoue K, Kato-Kogoe N, Ueno T.   +6 more
europepmc   +1 more source

Metabolic Alterations in Macrophage Subtypes Propel Immune and Stromal Remodeling in Neurofibroma's Malignant Progression

MedComm, Volume 7, Issue 4, April 2026.
Illustration of the microenvironment factors driving malignant progression in MPNSTs. ABSTRACT Neurofibromatosis type 1 (NF1) is characterized by the development of benign plexiform neurofibromas (PNFs). In 10%–15% of patients, these tumors undergo malignant transformation into aggressive malignant peripheral nerve sheath tumors (MPNSTs).
Ling‐Ling Ge, Yue‐Hua Li, Xuan Yu, Ming‐Yan Xing, Yi‐Hui Gu, Wei Wang, Jing‐Xuan Huang, Jun Liu, Hai‐Bing Zhang, Cheng‐Jiang Wei, Zhi‐Chao Wang, Qing‐Feng Li   +11 more
wiley   +1 more source

Calcifying nanoparticles induce apoptosis and calcification in bone marrow mesenchymal stem cells <i>via</i> the transforming growth factor-β/Smad pathway. [PDF]

World J Stem Cells
Su XL, Xu FR, Yang J, Niu SQ, Shi HJ, He YF, Li ZH, Bagari P, Wu XW, Peng XY, Zhang HW, Wang MY.   +11 more
europepmc   +1 more source

Pushing Frontiers for Proteoglycans

Proteoglycan Research, Volume 4, Issue 2, April 2026.
ABSTRACT Almost half of proteins have one or more post‐translational glycosylation modifications involving the addition of glycan structures. Proteoglycans are a class of glycosylated proteins with one or more glycosaminoglycan (GAG) chains covalently attached to the core protein.
Marissa L. Maciej‐Hulme
wiley   +1 more source

Targeting the Osteopontin-regulated PI3K/AKT signaling pathway: A molecular approach to overcome drug resistance and metastasis in gastrointestinal tumors. [PDF]

World J Gastrointest Oncol
Nian H, Bai Y, Wang HY, Yu H, Zhang ZL, Shi RH, Zhang S, Wu YB, Zhou DH, Du QC.   +9 more
europepmc   +1 more source

CD81 promotes proliferation and predicts survival in lung squamous cell carcinoma

Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.
Ryu Kanzaki, Steven Reid, Paulina Bolivar, Sara Larsson, Yasushi Shintani, Kristian Pietras   +5 more
wiley   +1 more source

Effects of Bone Morphogenetic Protein Agonist Small Molecule, SB4, on Osteogenic Differentiation of Adipose-Derived Mesenchymal Stem Cells. [PDF]

J Bone Metab
Naghshnejad F, Zeynali B, Shabani I, Tafreshi AP.   +3 more
europepmc   +1 more source

Hypoxia-Induced Osteopontin-Positive Glioma-Associated Macrophages Facilitate Glioma Mesenchymal Transition via NF-κB Pathway Activation. [PDF]

Cancer Commun (Lond)
Yang J, Li X, Zhu X, Li Z, Chen X, Huang R, Yu M, Han B, Jiang T, Zhang C, Liu X.   +10 more
europepmc   +1 more source