Results 181 to 190 of about 52,783 (282)

Osteogenic Activity of New Dammarane‐Type Saponins From Gynostemma pentaphyllum

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Isolation and determination of two new and three known dammarane‐type glycosides from the aerial parts of Gynostemma pentaphyllum with their osteogenic activity via stimulation of alkaline phosphatase (ALP) activity, collagen synthesis, and calcium mineralization in mouse osteoblastic MC3T3‐E1 cells.
Nguyen Tuan Duong, Tran Thi Thu Ha, Duong Thi Hai Yen, Do Thi Thao, Bui Huu Tai, Phan Van Kiem   +5 more
wiley   +1 more source

Bioactive Phytochemicals from <i>Artocarpus integer</i> Leaves Improve Bone-Related Outcomes in Ovariectomized Rats: An Integrated LC-HRMS, Network Pharmacology, and Experimental Study. [PDF]

Nutrients
Bahtiar A, Angie AN, Wahyuni T, Siriamornpun S.   +3 more
europepmc   +1 more source

Revising NHE‐1: From Cardiac Homeostasis to Heart Failure and Future Drug Development

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT NHE‐1 is a Na+/H+ exchanger that receives phosphorylation signals, binds calmodulin and responds to neurohormonal input from angiotensin II, endothelin‐1, and adrenergic pathways. In cardiac myocytes, NHE‐1 maintains pH homeostasis and couples to Na+/Ca2+ exchange and mitochondrial ion handling. During heart disease sustained activation drives
Vasileios Bouratzis, Nikoleta Douskou, Nikolaos P. Tzavellas, Yannis V. Simos, Petros Bozidis, Konstantinos I. Tsamis, Georgios S. Markopoulos, Dimitrios Peschos, Lampros Lakkas   +8 more
wiley   +1 more source

The Gut-Bone Axis: A Systematic Review on the Potential Intervention Pathways for Bone Health. [PDF]

Life (Basel)
Cantón-Cordeiro T, Shimochi S, Nakamura M, Puigbò P.   +3 more
europepmc   +1 more source

Report on the 13th international workshop on the CCN family of genes and inaugural ARBIOCOM conference, Nice, France

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Celebration of the 13th ICCNS meeting joint to the 1st ARBIOCOM Conference held on the site of Nice in December 2025. Abstract The 13th International Workshop on the CCN Family of Genes, held in Nice as part of the inaugural ARBIOCOM World Conference, brought together investigators with diverse research backgrounds, disciplines, and expertise. Building
Bernard Perbal, Ralf Weiskirchen, Annick Perbal, Brahim Chaqour   +3 more
wiley   +1 more source

Osteopontin mediates acquired resistance to hypoxia-inducing antiangiogenics and promotes anti-PD-L1 refractoriness in breast cancer models. [PDF]

J Clin Invest
Ruiz-Sepulveda JL, Bueno MJ, Mouron S, Jimenez-Renard V, Muñoz M, Moradiellos M, Garma LD, García-Jimeno L, Watson AW, Mouneimne G, Park S, Jimeno R, Quintela-Fandino M.   +12 more
europepmc   +1 more source

Critical role of cellular communication network factor 1 in early osteogenesis of mesenchymal stem cells primed by low‐intensity pulsed ultrasound and bone morphogenetic protein 2

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Cooperative stimulation of mechanical stress and osteoinductive factor, such as BMP‐2, enhances BMP signaling via the upregulation of BMP receptors. As a result, CCN1 production is increased and is secreted to the extracellular environment. Secreted CCN1 promotes Runx2 expression through interaction with integrin, leading to early osteogenic ...
Hsu Myat Paing, Satoshi Kubota, Masaharu Takigawa, Takuo Kuboki, Takashi Nishida   +4 more
wiley   +1 more source

Mesenchymal Stem Cells of Epicardial Adipose Tissue Show Differences in Immunophenotype and Osteogenic Potential in Patients with Coronary and Non-Coronary Heart Disease. [PDF]

Cells
Gruzdeva OV, Slesareva TA, Gorbatovskaya EE, Dolmatova SE, Dyleva YA, Fanaskova EV, Kokov AN, Nishonov AB, Barbarash OL.   +8 more
europepmc   +1 more source

Coordinated inflammatory macrophage and vascular smooth muscle cell remodeling signatures in human atherosclerosis: An integrative single‐cell and bulk transcriptomic analysis

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Integrative single‐cell and bulk transcriptomic analyses identified a highly inflammatory macrophage state and a vascular smooth muscle cell (VSMC) remodeling continuum in human atherosclerotic plaques. Candidate ligand‐receptor and ligand‐associated target gene expression patterns linked inflammatory macrophage activation with osteogenic/modulated ...
Xinyu Dong, Xuesong Hu, Qi Liu, Yuhao Dong, Yan Xuan, Muning Wang, Siyao Chang, Tianyi Lu, Zhiyang Han   +8 more
wiley   +1 more source

Role of IL-12 Levels in Diagnosing Tuberculosis Among People Living with HIV Receiving Antiretroviral Therapy. [PDF]

Int J Mol Sci
Shete A, Ghate M, Patil S, Shidhaye P, Mahajan B, Iwasaki-Hozumi H, Matsuba T, Hattori T.   +7 more
europepmc   +1 more source