Results 251 to 260 of about 99,821 (371)

Biomimetic Fibrinogen Nanofiber Scaffolds for Vascular Hematopoietic Stem Cell Niche Engineering

Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.
This study presents an advanced in vitro model of the vascular hematopoietic stem cell niche using self‐assembled fibrinogen nanofibers, mimicking the basement membrane in bone marrow (BM) sinusoids. The model supports the coculture of microvascular endothelial cells, stromal cells, and hematopoietic stem and progenitor cells, providing insights into ...
Sophia Lena Meermeyer, Arundhati Joshi, Constantin von Kaisenberg, Dorothea Brüggemann, Cornelia Lee‐Thedieck   +4 more
wiley   +1 more source

Calcifying nanoparticles induce apoptosis and calcification in bone marrow mesenchymal stem cells <i>via</i> the transforming growth factor-β/Smad pathway. [PDF]

World J Stem Cells
Su XL, Xu FR, Yang J, Niu SQ, Shi HJ, He YF, Li ZH, Bagari P, Wu XW, Peng XY, Zhang HW, Wang MY.   +11 more
europepmc   +1 more source

Therapeutic Targeting of Osteopontin in Breast Cancer Cells

, 2011
Champaka Gopal, Supriya Saraswati, Megha Sanyal, Anuradha Bulbule, Anuja Ramdasi, Dhiraj Kumar, Reeti Behera, Mansoor Ahmed, Goutam Chakraborty, Vinit Kumar, Shalini Jain, Swarnalata Gowrishankar, Pompom Ghosh   +12 more
openalex   +2 more sources

Engineering a Perfusion Bioreactor System for hiPSC‐Derived Progenitor Co‐Culture Capturing Microglial Features in CNS Development

Biotechnology and Bioengineering, Volume 123, Issue 2, Page 363-378, February 2026.
The authors report the development of a controlled and scalable 3D co‐culture system combining hiPSC‐derived erythromyeloid progenitors and neurospheres within the Ambr® 250 Modular platform operated with a newly designed perfusion system. This model faithfully recapitulates early microglia–neural interactions, enabling progenitor integration ...
Catarina M. Gomes, Inês de Sá, Margarida Delgado, Paula M. Alves, Catarina Brito   +4 more
wiley   +1 more source

Targeting the Osteopontin-regulated PI3K/AKT signaling pathway: A molecular approach to overcome drug resistance and metastasis in gastrointestinal tumors. [PDF]

World J Gastrointest Oncol
Nian H, Bai Y, Wang HY, Yu H, Zhang ZL, Shi RH, Zhang S, Wu YB, Zhou DH, Du QC.   +9 more
europepmc   +1 more source

Osteopontin in rheumatic diseases: A systematic review and meta-analysis

Stefano Zoroddu, Biagio Di Lorenzo, Panagiotis Paliogiannis, Arduino A. Mangoni, Ciriaco Carru, Angelo Zinellu   +5 more
openalex   +1 more source

Correlation Between Urinary Osteopontin Concentration and the Mineral Content and Composition of Kidney Stones. [PDF]

J Clin Med
Jaromin M, Kutwin P, Konecki T, Jerczyńska H, Wysocki P, Gajek M, Maniukiewicz W, Szynkowska-Józwik MI, Moczulski D.   +8 more
europepmc   +1 more source

Tumor expression of survivin, p53, cyclin D1, osteopontin and fibronectin in predicting the response to neo-adjuvant chemotherapy in children with advanced malignant peripheral nerve sheath tumor [PDF]

, 2018
Gabrielle Karpinsky, Małgorzata Krawczyk, Ewa Iżycka‐Świeszewska, Aleksandra Fatyga, Agnieszka Budka, Walentyna Balwierz, Grażyna Sobol, Beata Zalewska‐Szewczyk, Magdalena Rychłowska-Pruszyńska, Teresa Klepacka, Bożenna Dembowska–Bagińska, Bernarda Kazanowska, Anna Gabrych, Ewa Bień   +13 more
openalex   +1 more source

Metabolic reprogramming of efferocytosis in the tumour microenvironment: From apoptotic‐cell clearance to therapeutic targeting

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
This review systematically deconstructs the pathological efferocytic—metabolic axis in tumours, framing it as a three‐stage, self‐reinforcing cycle: from metabolite‐driven macrophage recruitment, through hijacked surface recognition, to post‐phagocytic metabolic reprogramming that locks in immunosuppression.
Qianlu Yang, Jie Yan, Qianxi Yang
wiley   +1 more source

B6C3F1 mice exposed to ozone with 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone and/or dibutyl phthalate showed toxicities through alterations of NF-kappaB, AP-1, Nrf2, and osteopontin

, 2004
Min Young Kim, Kyung Suk Song, Gun Ho Park, Seung H. Chang, Hyun‐Woo Kim, Jin‐hong Park, Hwa Jin, Kook Jong Eu, Hyun Sun Cho, Gami Kang, Young Chul Kim, Myung‐Haing Cho   +11 more
openalex   +1 more source