Results 61 to 70 of about 276,341 (309)

Expression of Concern on “A Radiographic Study on the Associations of Age and Prevalence of Vertebral Fractures with Abdominal Aortic Calcification in Japanese Postmenopausal Women and Men”

Journal of Osteoporosis, 2022
Journal of Osteoporosis
doaj   +1 more source

Heterogeneity in Lumbar Segmental Bone Mineral Density and Age‐Related Evolution of Whole‐Body Bone Mineral Density: Comprehensive Implications for Osteoporosis Risk Assessment

Orthopaedic Surgery
Objective This study aimed to analyze the bone mineral density (BMD) in various body regions, investigate the effects of age and sex on BMD, and characterize BMD variations among different lumbar segments (L1–L4).
Jia‐Jun Zhang, Xiong‐Yi Wang, Cheng‐Wei Weng, Miao Zheng, You‐Jia Xu   +4 more
doaj   +1 more source

Screening, prevention and management of osteoporosis among Canadian adults

Health Promotion and Chronic Disease Prevention in Canada, 2018
Introduction: This study provides a benchmark for the nationwide use of osteoporosis screening, prevention and management strategies among Canadians aged 40 years and older (40+) using data collected one year prior to the release of Osteoporosis Canada’s
Siobhan O’Donnell, Osteoporosis Surveillance Expert Working Group   +1 more
doaj   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

Advanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang, He Huang, Hongliang Dong, Qiang Ma, Hongyan Jin   +4 more
wiley   +1 more source

ROS Activated NETosis of Bone Marrow CD55+ Intermediate Mature Neutrophils Through HIF1α‐PADI4 Pathway to Initiate Bone Aging

Advanced Science, EarlyView.
In this study, we find CD55+ neutrophils show activated NETosis within bone marrow, induce BMSC senescence and osteogenesis inhibition, finally leading to bone aging initiation. Mechanistically, ROS synergizes with the CD55‐driven HIF1α‐PADI4 pathway to promote NETosis.
Yutong Guo, Shengjie Cui, Xi Wen, Yidi Wang, Ben Wu, Yixiang Wang, Yan Gu   +6 more
wiley   +1 more source

Impacts of Prior Anti-Osteoporosis Treatments on Sequential Denosumab Responses in BMD Changes Among Postmenopausal Osteoporosis Women in East China: Real-World Data Analysis

Clinical Interventions in Aging
Guoyu Guan,1 Yanping Du,2,* Wenjing Tang,2 Minmin Chen,2 Weijia Yu,2 Huilin Li,2 Qun Cheng2,* 1Department of Geriatrics, Huadong Hospital, Fudan University, Shanghai, People’s Republic of China; 2Department of Osteoporosis and Bone ...
Guan G, Du Y, Tang W, Chen M, Yu W, Li H, Cheng Q   +6 more
doaj  

Activity of Markers of Bone Metabolism in Animals with Simulated Osteoporosis after Dental Implantation [PDF]

, 2023
М. А. Даценко
openalex   +1 more source

DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss

Advanced Science, EarlyView.
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim, Kridtapat Sirisereephap, Hui Wang, Giulia Trimaglio, Kyoung‐Jin Chung, Jonathan Korostoff, Tetsuhiro Kajikawa, Xiaofei Li, Meircurius D.C. Surboyo, Tomoki Maekawa, Triantafyllos Chavakis, George Hajishengallis   +11 more
wiley   +1 more source

Guidelines for the Diagnosis and Treatment of Primary Osteoporosis (2022) [PDF]

Zhongguo quanke yixue, 2023
Chinese Society of Osteoporosis and Bone Mineral Research
doaj   +1 more source

TMEM131‐Mediated Soluble TRAIL Triggered Type II Alveolar Epithelial Cell Senescence in Radiation‐Induced Lung Injury

Advanced Science, EarlyView.
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han, Chunsheng Wang, Xiuli Guo, Yuan Luo, Jianguo Zhang, Fajian He, Zihang Zeng, Jiang Luo, Wen Ouyang, Yan Gong, Conghua Xie   +10 more
wiley   +1 more source