Results 281 to 290 of about 53,476 (305)

Osteoprotegerin and inflammation.

European cytokine network, 2003
RANK, RANKL, and OPG have well established regulatory effects on bone metabolism. RANK is expressed at very high levels on osteoclastic precursors and on mature osteoclasts, and is required for differentiation and activation of the osteoclast. The ligand, RANKL binds to its receptor RANK to induce bone resorption.
N, Saidenberg Kermanac'h, Natacha, Bessis, M, Cohen-Solal, M C, De Vernejoul, Marie-Christophe, Boissier   +4 more
openaire   +1 more source

Osteoprotegerin mitigates tail suspension-induced osteopenia

Bone, 2000
Osteoprotegerin (OPG) is a recently discovered protein related to the tumor necrosis factor receptor family. It has been shown to inhibit ovariectomy (ovx)-induced resorption in rats and increase bone mineral density in young mice. Tail suspension is a procedure that inhibits bone formation in maturing rodents. This study was designed to quantify OPG's
T A, Bateman, C R, Dunstan, V L, Ferguson, D L, Lacey, R A, Ayers, S J, Simske   +5 more
openaire   +2 more sources

Dietary Calcium and Osteoprotegerin

2015
Calcium is an essential trace element of human body. It is both the constructor and regulator of the body, and the source of our human life. Osteoprotegerin (OPG) is a glycoprotein involved in bone metabolism and plays a regulatory role in the immune, the skeletal and the circulatory systems.
Dianjun Sun, Jun Yu, Yanhui Gao, Yuanyuan Li   +3 more
openaire   +1 more source

Heritability of serum osteoprotegerin.

Annals of human genetics, 2011
Serum osteoprotegerin (OPG) level is a key biomarker for numerous traits of clinical importance like diabetes, coronary artery disease, blood pressure, lipid profile, and cancers, but its genetic basis remains poorly understood. We estimated the heritability (h(2)) of serum OPG level in 1442 southern Chinese subjects from 306 families.
Johnny S H, Kwan, Sumei, Xiao, Cora, Bow, Ching-Lung, Cheung, Cissy, Soong, Kam S, Lau, Pak C, Sham, Annie W C, Kung   +7 more
openaire   +4 more sources

Osteoprotegerin and Adhesion Molecules

2010
The glycoprotein osteoprotegerin (OPG) plays an important role in controlling normal bone remodelling by inhibiting osteoclast function. More recently, OPG has been implicated in a number of diseases associated with inflammation. This chapter describes current work being undertaken to try and understand the mechanisms underlying the association between
Rush, Catherine, Golledge, Jonathan
openaire   +1 more source

Osteoprotegerin sources examined

Nature Reviews Endocrinology, 2020
openaire   +2 more sources

The Role of Osteoprotegerin in Vascular Calcification and Bone Metabolism: The Basis for Developing New Therapeutics

Calcified Tissue International, 2019
L. Rochette, A. Méloux, E. Rigal, M. Zeller, G. Malka, Y. Cottin, C. Vergely   +6 more
semanticscholar   +1 more source

Osteoprotegerin

Annals of the Rheumatic Diseases, 2001
openaire   +2 more sources

Osteoprotegerin in Primary Hyperparathyroidism

Hormone and Metabolic Research, 2014
J, Szymczak, A, Bohdanowicz-Pawlak
openaire   +2 more sources

Osteoprotegerin in postmenopausal women

2003
Objective Osteoprotegerin has an important role in regulation of bone remodeling by blocking osteoclast differentiation, suppressing activation and stimulating its apoptosis. Altered production of osteoprotegerin is involved in the disorder of remodeling balance and bone loss in the postmenopause.
Kušec, Vesna, Jelčić, Jozo, Giljević, Zlatko, Kaštelan, Darko, Koršić, Mirko   +4 more
openaire   +2 more sources