Results 51 to 60 of about 491,654 (151)

Why Osteosarcopenia Matters: Clinical and Investigative Implications

European Journal of Clinical Investigation, Volume 56, Issue 5, May 2026.
Osteosarcopenia: Non‐pharmacological and pharmacological treatment strategies. ABSTRACT Background Osteosarcopenia, the combination of osteoporosis and sarcopenia, is a geriatric syndrome linked to functional decline, falls, and fragility fractures. The interaction among bone, muscle, and their shared pathophysiology is driven by mechanical, metabolic,
Erik Luiz Bonamigo, Marcella Nora Maia, Renata Pinheiro Cavallaro de Oliveira, Régis Gemerasca Mestriner, Ivan Aprahamian, Gustavo Duque   +5 more
wiley   +1 more source

Aging‐Driven Inter‐Organ Crosstalk in Postmenopausal Osteoporosis: From Immunometabolic Drift to Multisystem Frailty

The FASEB Journal, Volume 40, Issue 4, 28 February 2026.
Postmenopausal osteoporosis (PMOP) is increasingly recognized as an aging‐associated, multisystem state of fragility, in which estrogen deficiency exacerbates immune and metabolic drift across the bone marrow, skeletal muscle, adipose tissue, gut, vascular system, and neural circuits.
Xianlin Rao, Xiaoyu Cai
wiley   +1 more source

Osteosarcopenic obesity: the role of bone, muscle, and fat on health

Osteopenia/osteoporosis, sarcopenia, and obesity are commonly observed in the process of aging, and recent evidence suggests a potential interconnection of these syndromes with common pathophysiology.
Ilich JZ, Panton L, Purcell S, Folsom A, Ormsbee MJ, Prado CM, Siervo M   +6 more
core   +4 more sources

Prediabetes Associates With Musculoskeletal Alterations Independent of Total Body Adiposity

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Excess adiposity is a major risk factor for insulin resistance, prediabetes, and Type 2 diabetes and increases the risk for sarcopenia and osteosarcopenia later in life. It has been proposed that altered metabolic function and musculoskeletal status in people with obesity are directly linked, presumably because they share common ...
Alan Fappi, Clifton J. Holmes, Chao Cao, Vasavi Shabrish, Aman P. Aher, Karen Shen, Paul K. Commean, Dwight A. Towler, Dominic N. Reeds, Gretchen A. Meyer, Bettina Mittendorfer   +10 more
wiley   +1 more source

Influence of Resistance Training Variables to Improve Muscle Mass Outcomes in Sarcopenia: A Systematic Review With Meta‐Regressions

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Resistance training (RT) is the first‐line treatment to improve sarcopenia features. However, increasing muscle mass with RT remains challenging and displays inconsistent results. Manipulating training variables may present a novel approach to improve muscle mass gain in sarcopenic individuals. The present study aimed to measure the
Leo Delaire, Aymeric Courtay‐Breuil, Joannès Humblot, Hubert Vidal, Marc Bonnefoy, Emmanuelle Meugnier   +5 more
wiley   +1 more source

Sarcopenic obesity in males: from etiopathogenesis to therapeutic strategies in treatment

Клинический разбор в общей медицине
Sarcopenic obesity (SO) is a distinct phenotype of obesity characterized by the coexistence of excessive fat accumulation and reduced skeletal muscle mass and function.
Fatima K. Dzgoeva, Viktoria V. Demidova
doaj   +1 more source

OSTEOSARCOPENIC OBESITY: FREQUENCY AND ITS RELATION WITH FRAILTY AND PHYSICAL PERFORMANCE [PDF]

Innov Aging, 2017
Szlejf C, Parra-Rodríguez L, Rosas-Carrasco O.   +2 more
europepmc   +3 more sources

Four Dairy Products Mitigates Sarcopenia in Mice by Modulating Muscle Inflammation, Autophagy, and Protein Degradation

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
Dairy consumption, particularly goat fortified vitamin D and calcium low‐fat milk, could improve muscle mass and reduce fat weight in sarcopenic mice. Dairy consumption has the potential to improve muscle mass and prevent sarcopenia by modulating autophagy, reducing inflammation, and regulating gut microbiota.
Meng Sun, Tong Wu, Ruoyu Wang, Yuxin Ma, Yaxin Han, Yanmei Hou, Zhaofeng Zhang   +6 more
wiley   +1 more source

Prevalence and Associated Factors of Sarcopenic Obesity Among Nursing Home Residents: A Cross‐Sectional Multi‐Centre Study

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 3, June 2025.
ABSTRACT Background Obesity and sarcopenia are prevalent among older adults and associated with adverse health outcomes. The aims of the present study were to assess the prevalence of sarcopenic obesity, to evaluate the co‐occurence of sarcopenia, obesity and malnutrition (risk) and to assess the association between specific characteristics and ...
Doris Eglseer, Hristo Hristov, Sanja Krušič, Nadan Gregorič, Irena Hren, Igor Pravst, Živa Lavriša   +6 more
wiley   +1 more source

Body Mass Index Changes and Femur Fracture Risk in Parkinson's Disease: National Cohort Study

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 3, June 2025.
ABSTRACT Background Parkinson's disease (PD) increases fracture risk owing to postural instability and bone fragility, with femur fractures being the most frequent and clinically significant. Many patients with PD experience weight loss as the disease progresses, and low body mass index (BMI) is a well‐established fracture risk factor.
Sung‐Ho Ahn, Hye Sun Lee, Jun‐Hyuk Lee   +2 more
wiley   +1 more source