Dual transcriptomics of virus-host interactions: comparing two Pacific oyster families presenting contrasted susceptibility to ostreid herpesvirus 1. [PDF]
Background: Massive mortality outbreaks affecting Pacific oyster (Crassostrea gigas) spat in various countries have been associated with the detection of a herpesvirus called ostreid herpesvirus type 1 (OsHV-1).
Segarra A +10 more
europepmc +2 more sources
Towards a Mechanism for Poly(I·C) Antiviral Priming in Oysters
Viral diseases cause significant losses in aquaculture. Prophylactic measures, such as immune priming, are promising control strategies. Treatment of the Pacific oyster (Crassostrea gigas) with the double-stranded RNA analog poly(I·C) confers long-term ...
Nelson E. Martins
doaj +1 more source
Complete Genome Sequence of the Human Herpesvirus 6A Strain AJ from Africa Resembles Strain GS from North America. [PDF]
The genome sequence of human herpesvirus 6A (HHV-6A) strain AJ was determined in a comparison of target enrichment and long-range PCR using next-generation sequencing methodologies.
Spyrou, MA +5 more
core +1 more source
Killing of Kaposi's sarcoma-associated herpesvirus-infected fibroblasts during latent infection by activated natural killer cells. [PDF]
Kaposi's sarcoma-associated herpesvirus (KSHV) establishes life-long infection by evading clearance by the host immune system. In de novo infection and lytic replication, KSHV escapes cytotoxic T cells and NK cells through downregulation of MHC class-I ...
Nick C. Matthews +14 more
core +1 more source
A four year longitudinal sero-epidemiological study of bovine herpesvirus type-1 (BHV-1) in adult cattle in 107 unvaccinated herds in south west England [PDF]
Background: Bovine herpesvirus type-1 (BHV-1) is an important pathogen of cattle that presents with a variety of clinical signs, including the upper respiratory tract infection infectious bovine rhinotracheitis (IBR). A seroepidemiological study of BHV-
Ramírez Villaescusa, Ana +21 more
core +1 more source
The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin [PDF]
Tetherin (CD317/BST2) is an interferon-induced membrane protein that inhibits the release of diverse enveloped viral particles. Several mammalian viruses have evolved countermeasures that inactivate tetherin, with the prototype being the HIV-1 Vpu ...
Wilson, Sam J. +48 more
core +1 more source
Dual Analysis of Host and Pathogen Transcriptomes in Ostreid Herpesvirus 1 - Positive Crassostrea gigas [PDF]
Ostreid herpesvirus type 1 (OsHV-1) has become a problematic infective agent for the Pacific oyster Crassostrea gigas. In particular, the OsHV-1 μVar subtype has been associated with severe mortality episodes in oyster spat and juvenile oysters in France
VAROTTO, LAURA +11 more
core +1 more source
Spatial and temporal dynamics of mass mortalities in oysters is influenced by energetic reserves and food quality. [PDF]
Although spatial studies of diseases on land have a long history, far fewer have been made on aquatic diseases. Here, we present the first large-scale, high-resolution spatial and temporal representation of a mass mortality phenomenon cause by the ...
Fabrice Pernet +7 more
doaj +1 more source
Antiviral Defense and Innate Immune Memory in the Oyster
The Pacific oyster, Crassostrea gigas, is becoming a valuable model for investigating antiviral defense in the Lophotrochozoa superphylum. In the past five years, improvements to laboratory-based experimental infection protocols using Ostreid herpesvirus
Timothy J. Green, Peter Speck
doaj +1 more source
Partial characterisation of pilchard herpesvirus and the associated disease in pilchards [PDF]
In 1995 and again in 1998, millions of pilchards (Sardinops sagax neopilchardus) were found dead or dying off the coast of Australia and also in New Zealand. The epizootics moved progressively, at a rapid speed against the prevailing currents.
Crockford, Melanie
core

