Trained immunity and immune priming in plants and invertebrates [PDF]
eLifeImmune memory has long been thought to be restricted to the adaptive immune system of vertebrates. However, several lines of evidence have changed our understanding of immune memory and have shattered the strict separation between innate and adaptive ...
Joachim Kurtz +9 more
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Immune priming reshapes the microbiota and modulates pathogen dynamics in the Manila clam (Ruditapes philippinarum) [PDF]
Frontiers in MicrobiologyInvertebrates lack adaptive immunity and rely exclusively on innate defenses to combat pathogens. Recent studies have shown that invertebrates exhibit immune priming, a form of innate immune memory in which prior pathogen exposure enhances protection ...
Bruno K. Rodino-Janeiro +5 more
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No evidence for immune priming in ants exposed to a fungal pathogen.
PLoS ONE, 2012 There is accumulating evidence that invertebrates can acquire long-term protection against pathogens through immune priming. However, the range of pathogens eliciting immune priming and the specificity of the response remain unclear.
Anabelle Reber, Michel Chapuisat
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Immune priming in the insect gut: a dynamic response revealed by ultrastructural and transcriptomic changes [PDF]
BMC BiologyBackground Research on forms of memory in innate immune systems has recently gained momentum with the study of trained immunity in vertebrates and immune priming in invertebrates.
Moritz Baur +8 more
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Divergent immune priming responses across flour beetle life stages and populations
Ecology and Evolution, 2016 Growing evidence shows that low doses of pathogens may prime the immune response in many insects, conferring subsequent protection against infection in the same developmental stage (within‐life stage priming), across life stages (ontogenic priming), or ...
Imroze Khan, Arun Prakash, Deepa Agashe
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Gut bacteria induce heterologous immune priming in Rhodnius prolixus encompassing both humoral and cellular immune responses. [PDF]
PLoS PathogensInsects lack the adaptive, antibody mediated responses of vertebrates, yet they possess a robust innate immune system capable of defending themselves against pathogens.
Carissa A Gilliland +3 more
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Drosophila immune priming to Enterococcus faecalis relies on immune tolerance rather than resistance. [PDF]
PLoS Pathogens, 2023 Innate immune priming increases an organism's survival of a second infection after an initial, non-lethal infection. We used Drosophila melanogaster and an insect-derived strain of Enterococcus faecalis to study transcriptional control of priming.
Kevin Cabrera +4 more
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IMD-mediated innate immune priming increases Drosophila survival and reduces pathogen transmission. [PDF]
PLoS PathogensInvertebrates lack the immune machinery underlying vertebrate-like acquired immunity. However, in many insects past infection by the same pathogen can 'prime' the immune response, resulting in improved survival upon reinfection. Here, we investigated the
Arun Prakash +6 more
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Immune priming modulates Galleria mellonella and Pseudomonas entomophila interaction. Antimicrobial properties of Kazal peptide Pr13a [PDF]
Frontiers in ImmunologyGalleria mellonella larvae repeatedly infected with Pseudomonas entomophila bacteria re-induced their immune response. Its parameters, i.e. the defence activities of cell-free hemolymph, the presence and activity of antimicrobial peptides, and the ...
Michał Sułek +6 more
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Immune priming in Armadillidium vulgare against Salmonella enterica: direct or indirect costs on life history traits? [PDF]
ZooKeys, 2022 Invertebrate immune priming is defined as an enhanced protection against secondary pathogenic infections when individuals have been previously exposed to the same or a different pathogen.
Cybèle Prigot-Maurice +4 more
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