Results 61 to 70 of about 17,677 (248)
Matching theory for combinatorial geometries
, 1971 Given two combinatorial (pre-) geometries and an arbitrary binary relation between their point sets, a matching is a subrelation which defines a bijection between independent sets of the geometries.
Martin Aigner, Thomas A. Dowling
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
, 2000 In this thesis, we study neighbourhoods of exponential size that can be searched in polynomial time. Such neighbourhoods are used in local search algorithms for classes of combinatorial optimisation problems.
Congram, Richard K., Congram, R.K.
core
High throughput mechanical property testing of materials libraries using a piezoelectric [PDF]
, 2003 The present invention provides instruments and methods for screening combinatorial libraries that addresses many of the problems encountered when using conventional instruments.
Carlson, Eric D. +9 more
core
, 2023 For a positive integer $n$, the full transformation semigroup $T_n$ consists of all self maps of the set $\{1,\ldots,n\}$ under composition. Any finite semigroup $S$ embeds in some $T_n$, and the least such $n$ is called the (minimum transformation ...
Quinn-Gregson, Thomas +15 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Combinatorial Dichotomies in Set Theory
, 2011 We give an overview of a research line concentrated on finding to which extent compactness fails at the level of first uncountable cardinal and to which extent it could be recovered on some other perhaps not so large cardinal.
Stevo Todorcevic
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