Results 61 to 70 of about 28,393,246 (238)

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Lower bounds for incidences with hypersurfaces

open access: yesDiscrete Analysis, 2016
Lower bounds for incidences with hypersurfaces, Discrete Analysis 2016:16, 14pp. A fundamental result in combinatorial geometry, the Szemerédi-Trotter theorem, states that among any $n$ points and $m$ lines in $\mathbb R^2$ there can be at most $O((mn)^{
Adam Sheffer
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Definition of Intuitive Set Theory [PDF]

open access: yes, 2001
The two axioms which define intuitive set theory, Axiom of Combinatorial Sets and Axiom of Infinitesimals, are stated. Generalized Continuum Hypothesis is derived from the first axiom, and the infinitesimal is visualized using the ...
Nambiar, Kannan, Nambiar, K K
core  

Set Theory [PDF]

open access: yes
Set theory has experienced rapid development in the recent years, both in pure set theory and in its applications to other fields of mathematics. We have seen breakthroughs in combinatorial set theory, forcing, inner models, descriptive set theory, Borel

core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Optimal Combinatorial Electricity Markets

open access: yes, 2008
The deregulation of the electricity industry in many countries has created a number of marketplaces in which producers and consumers can operate in order to more effectively manage and meet their energy needs. To this end, this paper develops a new model
Jennings, N. R., Penya, Y.K.
core   +1 more source

The 0-1 inverse maximum stable set problem [PDF]

open access: yes
Given an instance of a weighted combinatorial optimization problem and its feasible solution, the usual inverse problem is to modify as little as possible (with respect to a fixed norm) the given weight system to make the giiven feasible solution optimal.
Yerim Chung, Marc Demange
core  

Topological Multi-groups and Multi-fields [PDF]

open access: yes, 2009
Topological groups, particularly, Lie groups are very important in differential geometry, analytic mechanics and theoretical physics. Applying Smarandache multi-spaces, topological spaces, particularly, manifolds and groups were generalized to ...
MAO, Linfan
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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