Results 21 to 30 of about 25,812,695 (293)

Live imaging of hair bundle polarity acquisition demonstrates a critical timeline for transcription factor Emx2

open access: yeseLife, 2020
Directional sensitivity of hair cells (HCs) is conferred by the aymmetric apical hair bundle, comprised of a kinocilium and stereocilia staircase. The mother centriole (MC) forms the base of the kinocilium and the stereocilia develop adjacent to it ...
Yosuke Tona, Doris K Wu
doaj   +1 more source

Genetic Hearing Loss Associated With Autoinflammation

open access: yesFrontiers in Neurology, 2020
Sensorineural hearing loss can result from dysfunction of the inner ear, auditory nerve, or auditory pathways in the central nervous system. Sensorineural hearing loss can be associated with age, exposure to ototoxic drugs or noise, or mutations in ...
Hiroshi Nakanishi   +10 more
doaj   +1 more source

Defining Dialogues: Tracing the Evolution of Human-Machine Communication [PDF]

open access: yes, 2023
This introduction to the volume discusses the evolving field of Human-Machine Communication (HMC), drawing on insights from the philosophy of science.
Edwards, Autumn   +4 more
core   +1 more source

The great tabu : a half century of population and family planning communication [PDF]

open access: yes, 1977
"This project was supported by the Office of Population, U.S. Agency for International Development, AID/csd-1059."For more about the East-West Center, see http://www.eastwestcenter.org/The author discusses the tabus on contraceptive and sex-related ...
Stycos, J. Mayone   +1 more
core   +1 more source

The Marshall Islands : history, culture and communication [PDF]

open access: yes, 1980
"Draft: Not for Quotation, Citation or Reproduction without Permission of Author."For more about the East-West Center, see https://www.eastwestcenter.org/Policy decisions about communication system resources are an important part of controlled ...
Runeborg, Ruth E.   +1 more
core   +1 more source

Synaptic mitochondria regulate hair-cell synapse size and function

open access: yeseLife, 2019
Sensory hair cells in the ear utilize specialized ribbon synapses. These synapses are defined by electron-dense presynaptic structures called ribbons, composed primarily of the structural protein Ribeye.
Hiu-tung C Wong   +5 more
doaj   +1 more source

Function of bidirectional sensitivity in the otolith organs established by transcription factor Emx2

open access: yesNature Communications, 2022
The inner ear is highly organized, with distinct domains being located across the Line of Polarity Reversal (LPR). Here they show that Emx2 establishes the LPR and bidirectional selectivity of otolith organs, and that loss of the LPR in mice affects ...
Young Rae Ji   +12 more
doaj   +1 more source

Cisplatin is retained in the cochlea indefinitely following chemotherapy

open access: yesNature Communications, 2017
Permanent hearing loss occurs in many cancer patients treated with cisplatin. In this study, the authors examine cisplatin pharmacokinetics in the cochleae of mice and humans showing that cisplatin is retained for months to years after treatment.
Andrew M. Breglio   +8 more
doaj   +1 more source

Single Cell and Single Nucleus RNA-Seq Reveal Cellular Heterogeneity and Homeostatic Regulatory Networks in Adult Mouse Stria Vascularis

open access: yesFrontiers in Molecular Neuroscience, 2019
The stria vascularis (SV) generates the endocochlear potential (EP) in the inner ear and is necessary for proper hair cell mechanotransduction and hearing.
Soumya Korrapati   +10 more
doaj   +1 more source

Chronic neurotransmission increases the susceptibility of lateral-line hair cells to ototoxic insults

open access: yeseLife, 2022
Sensory hair cells receive near constant stimulation by omnipresent auditory and vestibular stimuli. To detect and encode these stimuli, hair cells require steady ATP production, which can be accompanied by a buildup of mitochondrial byproducts called ...
Daria Lukasz, Alisha Beirl, Katie Kindt
doaj   +1 more source

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