Results 101 to 110 of about 611,402 (306)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Multidisciplinary Patterns of Interaction from Sciences to Computer Science
, 2006 Interaction is a fundamental dimension for modelling and engineering complex computational systems. More generally, interaction is a critical issue in the understanding of complex systems of any sorts: as such, it has emerged in several well-established ...
VIROLI, MIRKO +2 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The View from the Other Side: BE as a Computational Science Professional
Now in its tenth year, the Building Engagement Program connects students and researchers at mathematics and computational science conferences, with the goal of fostering the next generation of researchers in these fields. From modest beginnings at the SIAM CSE15 Conference in Salt Lake City, the program has evolved and grown, engaging with hundreds of ...
openaire +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Biolmg.org: A Catalog of Virtual Machine Images for the Life Sciences
Bioinformatics and Biology Insights, 2015 Virtualization is becoming increasingly important in bioscience, enabling assembly and provisioning of complete computer setups, including operating system, data, software, and services packaged as virtual machine images (VMIs).
Martin Dahlö +5 more
doaj +1 more source
Proceedings of the 25th Australasian Computing Education Conference, 2023 Shamima Nasrin Runa +3 more
openaire +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
, 2008 This is a technical report on the proceedings of the workshop held July 21 to July 25, 2008 at the American Institute of Mathematics, Palo Alto, California, organized by Joseph Landsberg, Lek-Heng Lim, Jason Morton, and Jerzy Weyman. We include a list of open problems coming from applications in 4 different areas: signal processing, the Mulmuley-Sohoni
openaire +2 more sources
Evaluation of live human-computer music-making: Quantitative and qualitative approaches
, 2009 NOTICE: this is the author’s version of a work that was accepted for publication in International Journal of Human-Computer Studies. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and ...
Stowell, D +3 more
core +1 more source