Results 121 to 130 of about 611,402 (306)

e-Science Infrastructure for the Social Sciences [PDF]

open access: yes
When the term „e-Science“ became popular, it frequently was referred to as “enhanced science” or “electronic science”. More telling is the definition ‘e-Science is about global collaboration in key areas of science and the next generation of ...
Ekkehard Mochmann
core  

The necessity of Computer Lessons up to the Grade 3 for Learning Nature Sciences

open access: yes, 2021
Diplomdarba “Datorikas kā atsevišķa mācību priekšmeta nepieciešamība skolēniem līdz 3. klasei dabaszinību apguvē” mērķis ir pierādīt, ka skolēniem datorika kā atsevišķs mācību priekšmets būtu apgūstams jau no 1.
Arāja-Bērziņa, Santa
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Prospects and Challenges for the Computational Social Sciences [Elektronisk resurs]

open access: yes, 2017
Computational social sciences (CSS) refer to computer-enabled investigations of human behaviour and social interaction. They include three main components - (i) computational modelling and social simulation, (ii) the analysis of digital traces of online
Bravo, Giangiacomo,, Farjam, Mike,
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

The relationship between game genres, learning techniques and learning styles in educational computer games

open access: yes, 2008
Educational computer game has many similar characteristics like any other genres of games. However its particular aspect is designed to teach, and in which main objective involves in learning a topic.
Wong, K.W.   +10 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Using Computer-Based Survey to Gather Knowledge Sharing Relationship Data

open access: yes, 2009
This paper focuses on the information technology used in specific data collection. As to the knowledge sharing, which is the important procedure of organizational knowledge management, previous researches regarded it as attribute data, but this paper has
Zhang Zheng, Zhou MingJie
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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