Results 111 to 120 of about 611,402 (306)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Distributed data storage: program of the course for students of specialty 122 “Computer sciences” of educational program “Computer sciences” of the second (master’s) level

The list of topics and key questions that will be considered during the study of the discipline, the list of competencies and learning outcomes by discipline, the procedure for evaluating learning outcomes and the distribution of points throughout the ...
Aleksiyev V.
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Do Computer Science Students Differ from Students of Other Fields of Study in Terms of Multiple Intelligences?

Informatics in Education
This paper presents survey results involving students from three fields of study (computer science, business, and pedagogy), positing that computer science students exhibit distinct patterns in the spectrum of multiple intelligences compared to students in social sciences disciplines.
Antoni Wilinski, Joanna Olkowicz, Sebastian Agata, Alicja Szostkiewicz, Szymon Guzik, Arkadiusz Wojtak, Paweł Tomkiewicz   +6 more
openaire   +2 more sources

Intelligent Information Systems in Management : Program of the course for students of specialty 122 "Computer sciences" of the study programme "Computer sciences" of the second (master's) level

The abstract of the course. Competencies and learning outcomes by discipline are given. The content of the course is presented by content modules and topics.
Zadachyn V. M.
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Deciphering the Role of Artificial Intelligence in Medical Sciences: An Update

National Board of Examinations Journal of Medical Sciences
Background: The utilization of Artificial intelligence (AI) computer systems is widespread globally, and the growing body of data in diverse scientific fields highlights the significance and requirement of computer-aided, advanced AI systems in ...
Siddhant Khanna, Merajul Haque Siddiqui, Shalini Bhushan, Rahul Saxena   +3 more
doaj   +1 more source

Avatars, Frankenstein, computer games, science fiction and otherness

, 2010
Legacy description not ...
openaire   +1 more source