Results 91 to 100 of about 48,533 (272)

On properties and constructions of t -designs, lambda -designs and perpendicular arrays

, 1991
Combinatorial configurations have significant applications in many areas, such as in the design of experiments, coding theory, computer architecture, and information storage and retrieval. In this work, we will concentrate on three types of combinatorial
Wu, Qiu-rong
core  

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Architecture Analysis and Benchmarking of 3D U-Shaped Deep Learning Models for Thoracic Anatomical Segmentation

IEEE Access
Recent rising interests in patient-specific thoracic surgical planning and simulation require efficient and robust creation of digital anatomical models from automatic medical image segmentation algorithms.
Arash Harirpoush, Amirhossein Rasoulian, Marta Kersten-Oertel, Yiming Xiao   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Microscopic Simulation-Based High Occupancy Vehicle Lane Safety and Operation Assessment: A Case Study

Journal of Advanced Transportation, 2018
This study proposes two general alternative designs to enhance the operation and safety of High Occupancy Vehicle (HOV) lanes at junctions with bus terminals or parking lots.
Chao Li, Mohammad Karimi, Ciprian Alecsandru   +2 more
doaj   +1 more source

Finite linear spaces consisting of two symmetric configurations

, 2005
We investigate finite linear spaces consisting of two symmetric configurations. A construction method using projective planes is presented, giving a possibly infinite number of examples.
Šiftar, Juraj, Krčadinac, Vedran, Vedran Krčadinac, Juraj Siftar, Juraj Šiftar   +4 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Optimising Ecological and Engineering Values in Coastal Protection via Combined Oyster Shell and Sand Bag Designs

, 2017
The increasing popularity of eco-engineering and living shorelines has seen oyster reefs suggested as a natural solution to erosion in low to moderate energy estuarine environments.
Felder, S ; https://orcid.org/, Coghlan, IR ; https://orcid.org/, Glamore, WC ; https://orcid.org/, Howe, D, Dunlop, T   +4 more
core   +1 more source