Results 91 to 100 of about 339,498 (258)
Feasibility Of One–Dedicated–Lane Bus Rapid Transit ⁄Light–Rail Systems And Their Expansion To Two–Dedicated–Lane Systems: A Focus On Geometric Configuration And Performance Planning, MTI Report 08-01 [PDF]
This report consists primarily of two parts, the first on feasibility and the next on space minimization. In the section on feasibility, we propose the concept of a Bus Rapid Transit (BRT) or light–rail system that effectively requires only one dedicated
Pratama, Agus +2 more
core +1 more source
Quadrature Points via Heat Kernel Repulsion
We discuss the classical problem of how to pick $N$ weighted points on a $d-$dimensional manifold so as to obtain a reasonable quadrature rule $$ \frac{1}{|M|}\int_{M}{f(x) dx} \simeq \frac{1}{N} \sum_{n=1}^{N}{a_i f(x_i)}.$$ This problem, naturally, has
Lu, Jianfeng +2 more
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Recent rising interests in patient-specific thoracic surgical planning and simulation require efficient and robust creation of digital anatomical models from automatic medical image segmentation algorithms.
Arash Harirpoush +3 more
doaj +1 more source
Impact of radiation dose on nuclear shuttle configuration [PDF]
The impact of nuclear radiation (from the NERVA propulsion system) on the selection of a reference configuration for each of two classes of the reusable nuclear shuttle is considered.
Billings, M. A., Goetz, C. A.
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
This study proposes two general alternative designs to enhance the operation and safety of High Occupancy Vehicle (HOV) lanes at junctions with bus terminals or parking lots.
Chao Li +2 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Estimation of Costs of Phosphorus Removal In Wastewater Treatment Facilities: Adaptation of Existing Facilities [PDF]
As part of a wider enquiry into the feasibility of offset banking schemes as a means to implement pollutant trading within Georgia watersheds, this is the second of two reports addressing the issue of estimating costs for upgrades in the performance of ...
D. Russell +4 more
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source

