Results 61 to 70 of about 339,498 (258)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Efficient Sizing and Layout Optimization of Truss Benchmark Structures Using ISRES Algorithm

Applied Sciences
This paper presents a comprehensive investigation into the application of the Improved Stochastic Ranking Evolution Strategy (ISRES) algorithm for the sizing and layout optimization of truss benchmark structures.
Muhammed Serdar Avcı, Demet Yavuz, Emre Ercan, Ayhan Nuhoğlu   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Synergistic effects of micro-hole injection and film cooling for increasing the cooling effectiveness: A numerical investigation

International Journal of Thermofluids
The continuous drive to improve the efficiency and power output of gas turbines has led to the need for advanced cooling strategies that can effectively dissipate high thermal loads.
Milad Mahdian Dowlatabadi, Saeed Rostami, Sepehr Sheikhlari, Khodayar Javadi   +3 more
doaj   +1 more source

Comparative Heat Transfer Performance of TPMS Structures: Spotlight on Fisch Koch S versus Gyroid, Diamond and SplitP Lattices [PDF]

E3S Web of Conferences
This study assesses the thermal behavior of different TPMS configurations, specifically examining the Fischer Koch S lattice in comparison to Gyroid, Diamond, and SplitP lattices.
Barakat Abdallah, Pan Yi, Sun BeiBei
doaj   +1 more source

Evaluation of the Influence of Reactor Design on the Treatment Performance of an Optimized Pilot-Scale Waste Stabilization Pond [PDF]

, 2013
Waste stabilization pond (WSP) is globally one of the most popular wastewater treatment options due to its high efficiency and low cost. A field scale prototype was designed and scaled down to a pilot-scale model using dimensional analysis in the ...
Olukanni, D. O.
core  

Resource Optimized Quantum Architectures for Surface Code Implementations of Magic-State Distillation

, 2019
Quantum computers capable of solving classically intractable problems are under construction, and intermediate-scale devices are approaching completion.
Chong, Frederic T., Ding, Yongshan, Franklin, Diana, Holmes, Adam, Javadi-Abhari, Ali, Martonosi, Margaret   +5 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

A Comparison of Closed-Loop Performance of Multirotor Configurations Using Non-Linear Dynamic Inversion Control

Aerospace, 2015
Multirotor is the umbrella term for the family of unmanned aircraft, which include the quadrotor, hexarotor and other vertical take-off and landing (VTOL) aircraft that employ multiple main rotors for lift and control.
Murray L. Ireland, Aldo Vargas, David Anderson   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source