Results 41 to 50 of about 236,240 (236)
Temperature log simulations in high-enthalpy boreholes
Geothermal Energy, 2019 Temperature logs have important applications in the geothermal industry such as the estimation of the static formation temperature (SFT) and the characterization of fluid loss from a borehole.
Jia Wang +3 more
doaj +1 more source
A FIC-based stabilized mixed finite element method with equal order interpolation for solid–pore fluid interaction problems [PDF]
, 2017 This is the peer reviewed version of the following article: [de-Pouplana, I., and Oñate, E. (2017) A FIC-based stabilized mixed finite element method with equal order interpolation for solid–pore fluid interaction problems. Int. J. Numer. Anal.
Oñate Ibáñez de Navarra, Eugenio +1 more
core +2 more sources
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Rheology of suspensions of viscoelastic spheres: deformability as an effective volume fraction
, 2018 We study suspensions of deformable (viscoelastic) spheres in a Newtonian solvent in plane Couette geometry, by means of direct numerical simulations. We find that in the limit of vanishing inertia the effective viscosity $\mu$ of the suspension increases
Brandt, Luca +2 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Solid-fluid dynamics of yield-stress fluids
, 2014 On the example of two-phase continua experiencing stress induced solid-fluid phase transitions we explore the use of the Euler structure in the formulation of the governing equations.
Grmela, Miroslav +2 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Vectorized numerical algorithms for the solution of continuum mechanics problems
Научно-технический вестник информационных технологий, механики и оптикиThe aim of the work is to study the possibilities provided by new information technologies, object-oriented programming tools and modern operating systems for solving boundary value problems of continuum mechanics described by partial differential ...
N. A. Brykov +2 more
doaj +1 more source
A coupled mitral valve -- left ventricle model with fluid-structure interaction
, 2017 Understanding the interaction between the valves and walls of the heart is important in assessing and subsequently treating heart dysfunction. With advancements in cardiac imaging, nonlinear mechanics and computational techniques, it is now possible to ...
Brown, André EX +11 more
core +3 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source