Results 51 to 60 of about 15,052 (259)

Vectorized numerical algorithms for the solution of continuum mechanics problems

Научно-технический вестник информационных технологий, механики и оптики
The aim of the work is to study the possibilities provided by new information technologies, object-oriented programming tools and modern operating systems for solving boundary value problems of continuum mechanics described by partial differential ...
N. A. Brykov, K. N. Volkov, V. N. Emelyanov   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Comparison of high-order methods on unstructured grids [PDF]

, 2013
A high-order Discontinuous Galerkin (DG) method is formulated and implemented on the Cranfield University’s 3D unstructured Finite Volume Method (FVM) code (UCNS3D), for both linear and non-linear hyperbolic conservation laws and for test-cases which ...
Iqbal, Kashif H.
core  

Deterministic numerical solutions of the Boltzmann equation using the fast spectral method [PDF]

, 2013
The Boltzmann equation describes the dynamics of rarefied gas flows, but the multidimensional nature of its collision operator poses a real challenge for its numerical solution. In this paper, the fast spectral method [36], originally developed by Mouhot
Reese, Jason M., White, Craig, Scanlon, Thomas J., Zhang, Yonghao, Scanlon, Thomas, Wu, Lei, Reese, Jason   +6 more
core   +1 more source

Review of unified gas-kinetic scheme and its wave-particle approach

Kongqi donglixue xuebao
Unlike traditional computational fluid dynamics (CFD), which is constrained by the conventional framework of discretizing partial differential equations (PDEs), the core idea of direct modeling approach is the integration of the cell-grid size as the ...
Xiaojian Yang, Junzhe Cao, Kun Xu, Kun Xu   +3 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

One and two-fiber orientation kinetic theories of fiber suspensions [PDF]

, 2013
http://dx.doi.org/10.1016/j.jnnfm.2012.10.009The morphology influencing rheological properties of suspensions of rigid spheres constitutes the flow induced collective ordering of the spheres characterized by two or more sphere distribution functions ...
GRMELA, Miroslav, CHINESTA SORIA, Francisco, Chinesta, Francisco, AMMAR, Amine   +3 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

High-order methods for steady, unsteady and transitional flow over a cylinder [PDF]

, 2012
In this thesis, the flow around a cylinder is chosen as a test case for higher-order numerical reconstruction techniques. No direct comparison of these higher-order methods has been carried out for this particular test case.
Starr, Maxwell
core