Results 71 to 80 of about 15,052 (259)
Machine Learning Reshaping Computational Fluid Dynamics: A Paradigm Shift in Accuracy and Speed
FluidsAccurate and efficient CFD simulations are essential for a wide range of engineering and scientific applications, from resilient structural design to environmental analysis.
Aly Mousaad Aly
doaj +1 more source
Advances in Unsteady Dynamics of Secondary Flow in 90° Pipe Bends [PDF]
长江科学院院报[Objective] The unsteady motion of secondary flow, namely Dean vortices, in bent pipes can induce thermal fatigue and mechanical fatigue, posing a serious threat to the safe operation of industrial piping systems.
WANG Zhi-xin, HAN Song-lin, JIANG Zhi-bing
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Investigations of smoothed particle hydrodynamics method for fluid-rigid body interactions
, 2013 The aim of this project is to investigate the capability of smoothed particle hydrodynamics (SPH) method for fluid-rigid body interactions. SPH is one of the most widely used meshless methods which use particles to represent the system.
Sun, Fanfan
core
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Eulerian modelling and computational fluid dynamics simulation of mono and polydisperse fluidized suspension [PDF]
, 2008 This research project is concerned with the Eulerian-Eulerian mathematical modelling of fluidized suspensions. We first derive new averaged equations of motion for particulate systems made up of a finite number of monodisperse particle classes; this ...
Mazzei, L., Mazzei, L
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
MathematicsThis study investigates the fractional-order Sawada–Kotera and Rosenau–Hyman equations, which significantly model non-linear wave phenomena in various scientific fields.
Khudhayr A. Rashedi +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
A: Universality in Vortex Formation. B: Evaluation of Mach Wave Radiation Mechanisms in a Supersonic Jet [PDF]
, 2000 In this thesis two distinct features of coherent structures are investigated. In Part I a model for the pinch-off process in vortex ring formation is developed.
Mohseni, Kamran
core +1 more source