Results 61 to 70 of about 1,100,119 (264)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Race-Related Research in Economics and Other Social Sciences [PDF]

open access: yes
Center for Law & Economics Working Paper Series, 2021 (06)
Advani, Arun   +3 more
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

A Quantitative Analysis of Seaplane Accidents from 1982-2021

open access: yesInternational Journal of Aviation, Aeronautics, and Aerospace
This study aimed to assess and analyze all historical National Transportation Safety Board accident reports since 1982. For analysis, reports were bisected into seaplane (float, amphibian, and hull) and non-seaplane groups.
David C. Ison
doaj   +1 more source

Topics related to social sciences by authors from Slovenia in agriculture-and-life-sciences database CAB Abstracts

open access: yesActa Agriculturae Slovenica, 2011
Documents related to social sciences are processed/indexed by several field-specific (e.g. Sociological Abstracts) and general (Web of Science, Scopus) bibliographic databases.
Tomaž BARTOL, Marjan HOČEVAR
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Social behaviour in the Age of Empathy? – A social scientist’s perspective on current trends in the behavioural sciences.

open access: yesFrontiers in Human Neuroscience, 2013
Recently, several behavioral sciences became increasingly interested in investigating biological and evolutionary foundations of (human) social behavior. In this light, prosocial behavior is seen as a core element of human nature.
Svenja eMatusall
doaj   +1 more source

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