Results 101 to 110 of about 1,551,395 (273)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Developing and testing a framework for coding general practitioners’ free-text diagnoses in electronic medical records - a reliability study for generating training data in natural language processing

BMC Primary Care
Background Diagnoses entered by general practitioners into electronic medical records have great potential for research and practice, but unfortunately, diagnoses are often in uncoded format, making them of little use.
Audrey Wallnöfer, Jakob M. Burgstaller, Katja Weiss, Thomas Rosemann, Oliver Senn, Stefan Markun   +5 more
doaj   +1 more source

Interaction of Industry Development with its Encoding in Rceat: Experience of Veterinary Medication Production

Вестник Российского экономического университета имени Г. В. Плеханова
In public space prospects of development of industries in Russian economy that put out new goods and services are often connected with giving these industries relative codes in the Russian Classifier of Economic Activity Types (RCEAT).
G. M. Samoilov
doaj   +1 more source

The Connotative Meaning of the Visual Sign of Tokek (Gekko Gecko) on the T-Shirt Used as a Souvenir in Lombok, West Nusa Tenggara [PDF]

, 2012
The background of the study was the use of the visual sign of tokek (Gekko gecko) used in various souvenirs, one of which was T-shirt, in Lombok.
NURUL, KEMALA DEWI
core  

Cool star model atmospheres for Gaia : ATLAS, MARCS, and PHOENIX

, 2011
International audienceI present the widely used model atmosphere codes ATLAS, MARCS, and PHOENIX, and I compare their output model structures and spectra for cool stars of FGKM-types.
Plez, Bertrand
core   +4 more sources

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Outcomes of Primary Endodontic Therapy Provided by Endodontic Specialists Compared with Other Providers [PDF]

, 2016
Introduction The objective of this study was to compare the outcomes of initial nonsurgical root canal therapy for different tooth types provided by both endodontists and other providers.
Bhagavatula, Pradeep, Burry, Jacob, Eichmiller, Fredrick, Stover, Sheila E.   +3 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Multilevel Coded Modulation for Unequal Error Protection and Multistage Decoding—Part II: Asymmetric Constellations [PDF]

, 1999
In this paper, multilevel coded asymmetric modulation with multistage decoding and unequal error protection (UEP) is discussed. These results further emphasize the fact that unconventional signal set partitionings are more promising than traditional ...
Fossorier, Marc P. C., Imai, Hideki, Isaka, Motohiko, Lin, Shu, Morelos-Zaragoza, Robert H   +4 more
core   +3 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source