Results 91 to 100 of about 171,145,466 (283)

Enhancing description of hospital-conditions with ICD-11 cluster coding: Better codes for monitoring and prevention

International Journal of Population Data Science, 2018
Introduction Exposure to health care events sometimes has unintended and undesired consequences. Health care and complications arising in the course of care are diverse and complex. Representing them comprehensively in information systems is challenging,
Danielle Southern, Catherine Eastwood, Hude Quan, William Ghali   +3 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

CoBRA: Controlled Rendering and Annotation of Barcode Images Applied to the Cylindrical Surfaces

International Journal of Computational Intelligence Systems
QR Codes seem to be the most popular form of machine readable data representation. However, their presence on cylindrical surfaces, like bottles and cans, often complicates scanning.
Vladimir Karnaushko, Pavel Bezmaternykh, Dmitriy Polevoy, Konstantin Bulatov   +3 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Having a Great Number of Codes in Glaserian Classic Grounded Theory

Grounded Theory Review: An International Journal
In Glaserian classic grounded theory, there is an expectation that a researcher will have a great number of codes (and memos) during a study as data are analyzed. While having many descriptive ideas may be acceptable in other designs, during open coding,
Barry Chametzky
doaj  

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Iterative Construction of Reversible Variable-Length Codes and Variable-Length Error-Correcting Codes

, 2004
We propose a generic algorithm for the construction of efficient reversible variable-length codes (RVLCs) and variable-length error-correcting (VLEC) codes, which optimizes the codeword length distribution.
Wang, J., Yang, L-L., Hanzo, L.
core   +1 more source

Mixed-Methods Evaluation of Massachusetts’ Neonatal Abstinence Syndrome Surveillance System, 2020–2022

AJPM Focus
Introduction: The Massachusetts Department of Public Health established neonatal abstinence syndrome surveillance as an active, state-wide, population-based system using the Council of State and Territorial Epidemiologists (Tier 1) neonatal abstinence ...
Alyssa M. Pochkar, MPH, Hanna M. Shephard, MPH, Mahsa M. Yazdy, PhD, Eirini Nestoridi, MD   +3 more
doaj   +1 more source

The 3A non-structural-protein coding region of the southern African SAT type isolates differs from that of other foot-and-mouth disease viruses.

The Onderstepoort journal of veterinary research, 2002
The 3A non-structural protein of foot-and-mouth disease viruses is a relatively conserved protein comprising 153 amino acids. Recent studies have demonstrated correlation between mutations in the 3A non-structural-protein-coding region, including a 10-amino acid deletion, and attenuation of the viruses in cattle.
L E, Heat, H G, Van Rensburg, W, Vosloo, L H, Nel   +3 more
openaire   +1 more source