Results 71 to 80 of about 171,145,466 (283)

Assessment of cancer risk associated with 7‐nitroso‐3‐(trifluoromethyl)‐5,6,7,8‐tetrahydro[1,2,4] triazolo‐[4,3‐a]pyrazine‐contaminated sitagliptin use: A retrospective cohort study

open access: yesJournal of Diabetes Investigation
Aims/Introduction A recent US Food and Drug Administration report highlighted concerns over nitrosamine (7‐nitroso‐3‐(trifluoromethyl)‐5,6,7,8‐tetrahydro[1,2,4] triazolo‐[4,3‐a]pyrazine [NTTP]) impurities in sitagliptin, prompting investigations into its
Takehiro Sugiyama   +11 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Describing quaternary codes using binary codes [PDF]

open access: yes, 2011
PhDFor a quaternary code C of length n, de ne a pair of binary codes fC1;C2g as: -C1 = C mod 2 -C2 = h(C \ 2Zn 4 ) where h is a bijection from 2Z4 to Z2 mapping 0 to 0 and 2 to 1 and for the extension to a map acting coordinatewise.
Al Kharoosi, Fatma Salim Ali
core  

Positive predictive value of ICD-10 codes for acute myocardial infarction in Japan: a validation study at a single center

open access: yesBMC Health Services Research, 2018
Background In Japan, several large healthcare databases have become available for research since the early 2000’s. However, validation studies to examine the accuracy of these databases remain scarce.
Takashi Ando   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Ownership and Property in Communist Civil Codes of Czechoslovakia

open access: yesActa Iuris Stetinensis, 2019
The distribution of property in society is a fundament of communist ideology, which in Czechoslovakia was regulated by two Civil Codes. In the process of reforming the entire legal system, the purpose of both codes was, besides property regulation, also ...
Petr Bělovský
doaj   +3 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

On spectra of BCH codes [PDF]

open access: yes, 1995
Derives an estimate for the error term in the binomial approximation of spectra of BCH codes. This estimate asymptotically improves on the bounds by Sidelnikov (1971), Kasami et al. (1985), and Sole (1990)
Krasikov, I   +3 more
core   +1 more source

Performance Evaluation of Selected Serial Concatenation Codes in AWGN & Frequency Selective Rayleigh Fading Channels

open access: yesJournal of Engineering and Sustainable Development, 2011
Concatenation codes have attracted a great deal of interest since their discovery. They have been successfully used in digital communication systems in order to achieve reliable transmission on a noisy channel.
Amel M. Noori, Hikmat N. Abdullah
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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