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Audiological Monitoring for Ototoxicity in Medically Fragile Children
Seminars in Hearing, 2011Risk for hearing loss due to medical interventions has audiological as well as medicolegal implications. In children with life-threatening conditions, medical interventions may require great risk of morbidity to reduce mortality. Although audiologists are typically not in the position of intervening to rescue hearing, they do provide necessary and ...
Brian Fligor, Charlotte Mullen
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High-Frequency Audiometric Monitoring for Early Detection of Aminoglycoside Ototoxicity
The Journal of Infectious Diseases, 1992Treatment with aminoglycosides is known to cause irreversible hearing loss, typically affecting higher-frequency hearing first and progressing to lower frequencies. Standardized methodology has not been developed for early detection of ototoxicity. Serial conventional (0.25-8 kHz) and high-frequency (9-20 kHz) hearing threshold monitoring was done ...
S A, Fausti +5 more
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Otoacoustic emissions — an approach for monitoring aminoglycoside induced ototoxicity in children
International Journal of Pediatric Otorhinolaryngology, 1999The early detection of hearing impairment caused by ototoxic drugs, such as aminoglycosides, has been the aim of research world-wide. Histopathological studies have shown that the outer hair cells are the most susceptible cochlear components to injury from ototoxic drugs like aminoglycosides.
P, Stavroulaki +5 more
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Audiologic Monitoring of Ototoxicity
2014Ototoxicity can be defined as the capacity of a drug or chemical to cause damage to the inner ear structure and\or function. This phenomenon may involve the cochlea, vestibule or both. The symptoms of ototoxicity include hearing loss, tinnitus, and vertigo. Today, the number of audiologic tests for monitoring ototoxicity has increased.
TAŞ, Abdullah, YAĞIZ, Recep
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Cisplatin-induced ototoxicity: the current state of ototoxicity monitoring in New Zealand.
2011Background: Many well-known pharmacologic agents have been shown to have toxic effects to the cochleo-vestibular system. Examples of such ototoxic agents include cisplatin and aminoglycoside antibiotics. Ototoxicity monitoring consists of a comprehensive pattern of audiological assessments designed to detect the onset of any hearing loss.
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Poster presentations, 2018
Objectives Cisplatin, despite its effectiveness against various malignancies, can lead to serious side effects such as ototoxicity. However, ototoxicity monitoring has been shown inconsistent during drug treatment for adults.
M. Rhainds +4 more
semanticscholar +1 more source
Objectives Cisplatin, despite its effectiveness against various malignancies, can lead to serious side effects such as ototoxicity. However, ototoxicity monitoring has been shown inconsistent during drug treatment for adults.
M. Rhainds +4 more
semanticscholar +1 more source
High-Frequency Audiometric Monitoring Strategies for Early Detection of Ototoxicity
Ear and Hearing, 1994Therapeutic drugs such as the aminoglycoside antibiotics (AMG) and the chemotherapy agent cisplatin (CDDP) are known to cause irreversible hearing loss, typically affecting highest frequency hearing first with progression of loss to the lower frequency regions.
Fausti, Stephen A. +5 more
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[Monitoring drug ototoxicity with distortion products].
Acta otorrinolaringologica espanola, 2000Distortion products are currently considered an objective method for rapidly evaluating the functional status of the cochlea, which is interesting for the monitoring of drug ototoxicity. We studied 40 ears from patients who had received an ototoxic drug, tobramycin.
M, Orts Alborch +5 more
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Audiologic Threshold Monitoring of Patients Receiving Ototoxic Drugs
Annals of Otology, Rhinology & Laryngology, 1989An effort was made to determine the efficacy of auditory threshold monitoring of patients receiving ototoxic drugs. Forty-four patients treated with either tobramycin or vancomycin for osteomyelitis were tested at the beginning of treatment, following treatment, and twice weekly during treatment when possible.
W L, Meyerhoff +3 more
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Gentamicin-induced ototoxicity in a carefully monitored renal-failure patient
American Journal of Health-System Pharmacy, 1981A case of gentamicin-induced ototoxicity, documented by electronystagmography and audiometry, in a patient with chronic renal failure is presented. A 39-year-old white man was hospitalized for a renal transplant procedure. Multiple postoperative complications included infection, and the transplanted kidney was rejected eventually.
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