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The Importance of High-Tone Audiometry in Monitoring for Ototoxicity
Archives of Oto-rhino-laryngology, 1985Early detection of ototoxicity is of vital importance in cases in which ototoxic drugs are administered. Ototoxicity as a result of cis-platinum administration is well documented. Auditory damage may be reduced by changes in dose, drugs or methods of treatment. As ototoxicity appears to be most pronounced in the higher frequencies of sound, any changes
R A Tange
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Audiologic Monitoring for Ototoxicity
Otolaryngologic Clinics of North America, 1993In summary, the clinician has a variety of protocols available for monitoring ototoxicity. Depending on the patient's risk factors and ability to be tested, the protocol for a given patient may vary. A flow chart reflecting some of the possible decisions and options is presented in Figure 1.
K C, Campbell, J, Durrant
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The use of tele-audiology in ototoxicity monitoring: A scoping review
Journal of Telemedicine and Telecare, 2022Introduction Due to the growing burden of disease in South Africa, encompassing conditions such as tuberculosis, human immunodeficiency virus, and cancer, the holistic management of affected patients incorporating ototoxicity monitoring is a necessity.
Nazeera Peerbhay +4 more
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Audiometric monitoring of cis-platinum ototoxicity
Gynecologic Oncology, 1983A prospective study was performed on 37 patients receiving 50 mg/m2 of cis-platinum every 3 to 4 weeks. These patients received a baseline audiogram evaluation and subsequent testing before each dose. Ototoxicity was noted to occur in 46% of the patients during therapy. Fourteen percent of this group showed a hearing loss in the speech frequency range.
R L, Brown +3 more
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Drug-Induced Ototoxicity: Diagnosis and Monitoring
Drug Safety, 2018Ototoxicity diagnosis and management has historically been approached using a variety of methods. However, in recent years a consensus on useful and practical approaches has been developed through clinical guidelines of the American Speech Language Hearing Association, the American Academy of Audiology, and multiple clinical trials published in peer ...
Kathleen C M, Campbell +1 more
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Ototoxicity Monitoring: Program Approaches and Considerations
Seminars in Hearing, 2011Dawn Konrad-Martin +2 more
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Challenges in Ototoxicity Monitoring in the Pediatric Oncology Population
Journal of the American Academy of Audiology, 2014Background:Platinum-based chemotherapy and cranial radiation are effective treatment options commonly prescribed for a variety of childhood cancers. These therapies can, and often do, result in early- and late-onset adverse health effects such as hearing loss.
Johnnie K, Bass, Shaum P, Bhagat
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Vestibular Ototoxicity: The Importance and Pragmatics of Monitoring
Seminars in Hearing, 2011exaly +2 more sources
Ototoxicity: mechanisms, protective agents, and monitoring
Current Opinion in Otolaryngology & Head and Neck Surgery, 2000In the past year, progress has been made not only in elucidating the mechanisms of ototoxicity but also in finding otoprotective agents. For aminoglycosides, new dosing protocols and protective agents, including growth factors and salicylates, show promise for eventually reducing ototoxicity ...
Kathleen C.M. Campbell +2 more
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