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Ouchterlony Double Immunodiffusion Method Demonstrates Absence of Ferritin Immunoreactivity in Visceral Organs from Nine Patients with Niemann-Pick Disease Type C

open access: closedBiochemical and Molecular Medicine, 1996
Ouchterlony double immunodiffusion clearly demonstrated absence of ferritin, the principal iron storage protein, in spleen and/or liver extracts from nine patients with Niemann-Pick disease type C (NPC). The patients died from different clinical forms of this disease of still unknown etiology.
H, Christomanou, K, Harzer
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