Measuring out-of-field dose to the hippocampus in common radiotherapy indications [PDF]
Radiation Oncology, 2023 Background The high susceptibility of the hippocampus region to radiation injury is likely the causal factor of neurocognitive dysfunctions after exposure to ionizing radiation.
Hendrik Auerbach +4 more
doaj +5 more sources
Out-of-field dose in stereotactic radiotherapy for paediatric patients [PDF]
Physics and Imaging in Radiation Oncology, 2021 Background and purpose: Stereotactic radiotherapy combines image guidance and high precision delivery with small fields to deliver high doses per fraction in short treatment courses.
Lachlan Garrett +5 more
doaj +7 more sources
Validation of a Monte Carlo Framework for Out-of-Field Dose Calculations in Proton Therapy [PDF]
Frontiers in Oncology, 2022 Proton therapy enables to deliver highly conformed dose distributions owing to the characteristic Bragg peak and the finite range of protons. However, during proton therapy, secondary neutrons are created, which can travel long distances and deposit dose
Marijke De Saint-Hubert +35 more
doaj +12 more sources
The out-of-field dose in radiation therapy induces delayed tumorigenesis by senescence evasion [PDF]
eLife, 2022 A rare but severe complication of curative-intent radiation therapy is the induction of second primary cancers. These cancers preferentially develop not inside the planning target volume (PTV) but around, over several centimeters, after a latency period ...
Erwan Goy +20 more
doaj +6 more sources
Out-of-Field Dose Measurement by TLD Dosimetry and Estimation of Radiation-Induced Secondary Cancer Risk of Thyroid and Breast from Head Radiotherapy [PDF]
Journal of Biomedical Physics and Engineering, 2023 Background: Radiation therapy, the most common form of cancer treatment, can result in late complications, such as secondary breast and thyroid cancers.Objective: This study aimed to evaluate the risk of secondary cancers using two radiobiological models
Shiva Rahbar Yazdi +2 more
doaj +3 more sources
Experimental Validation of an Analytical Program and a Monte Carlo Simulation for the Computation of the Far Out-of-Field Dose in External Beam Photon Therapy Applied to Pediatric Patients [PDF]
Frontiers in Oncology, 2022 BackgroundThe out-of-the-field absorbed dose affects the probability of primary second radiation-induced cancers. This is particularly relevant in the case of pediatric treatments.
Marijke De Saint-Hubert +20 more
doaj +3 more sources
Out-of-field dose calculation by a commercial treatment planning system and comparison by monte carlo simulation for varian TrueBeam® [PDF]
Journal of Medical Physics, 2019 Purpose: The calculation accuracy of treatment planning systems (TPSs) drops drastically when the points outside the field edges are considered. The real accuracy of a TPS and linear accelerator (linac) combination for regions outside the field edge is a
N S Shine +4 more
doaj +3 more sources
Analytical models for external photon beam radiotherapy out-of-field dose calculation: a scoping review [PDF]
Frontiers in Oncology, 2023 A growing body of scientific evidence indicates that exposure to low dose ionizing radiation (< 2 Gy) is associated with a higher risk of developing radio-induced cancer.
Nathan Benzazon +14 more
doaj +2 more sources
Out-of-field dose assessment for a 1.5 T MR-Linac with optically stimulated luminescence dosimeters. [PDF]
Med Phys, 2021 Purpose To assess the out‐of‐field surface and internal dose of the 1.5 T MR‐Linac compared to the conventional external beam linac using optically stimulated luminescence dosimeters (OSLDs), and evaluate the out‐of‐field dose calculation accuracy of the
Zhang Y +8 more
europepmc +2 more sources
Study of out-of-field dose in photon radiotherapy: A commercial treatment planning system versus measurements and Monte Carlo simulations. [PDF]
Med Phys, 2020 Purpose An accurate assessment of out‐of‐field dose is necessary to estimate the risk of second cancer after radiotherapy and the damage to the organs at risk surrounding the planning target volume.
Sánchez-Nieto B +4 more
europepmc +2 more sources