Results 81 to 90 of about 168,547,723 (230)

Out-of-field teachers knowing, learning and doing mathematics [PDF]

open access: yes, 2023
This thesis considers how out-of-field teachers of mathematics conceptualise knowing and learning mathematics and why they value doing it. Out-of-field teachers are those whose degree and professional qualifications are in subjects other than the one ...
Yardley, F.
core  

Editorial: Out-of-field second primary cancer induction: Dosimetry and modelling

open access: yesFrontiers in Oncology, 2022
Beatriz Sánchez-Nieto   +6 more
doaj   +1 more source

A study on out-of-field leakage of an accelerator-based neutron beam for boron neutron capture therapy

open access: yesFrontiers in Oncology
More and more accelerator-based boron neutron capture therapy (AB-BNCT) facilities are under the construction or commissioning stage, and the neutron beam characteristic measurements at each facility will start soon.
Zhen-Fan You   +2 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Photon and Neutron Dose Estimation Using Monte Carlo Simulation in TrueBeam’s Room

open access: yesJournal of Medical Physics
Purpose: The distribution of neutron ambient dose equivalent within the TrueBeam 10 MV photon chamber was investigated. Materials and Methods: The research used particle and heavy ion transport code system (PHITS) code and JENDL-5.0 to simulate the ...
Soai Dang Quoc   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Integral T-Shaped Phantom-Dosimeter System to Measure Transverse and Longitudinal Dose Distributions Simultaneously for Stereotactic Radiosurgery Dosimetry

open access: yesSensors, 2012
A T-shaped fiber-optic phantom-dosimeter system was developed using square scintillating optical fibers, a lens system, and a CMOS image camera.
Bongsoo Lee   +8 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

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