Results 31 to 40 of about 32,094 (189)

Haplotypic QTL mapping in an outbred pedigree

Genetical Research, 2003
An offspring genome can be viewed as a mosaic of chromosomal segments or haplotypes contributed by multiple founders in any quantitative trait locus (QTL) detection study but tracing these is especially complex to achieve for outbred pedigrees. QTL haplotypes can be traced from offspring back to individual founders in outbred pedigrees by combining ...
David P, Gwaze, Yi, Zhou, M Humberto, Reyes-Valdés, Mohammad A, Al-Rababah, Claire G, Williams   +4 more
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Extended tracts of homozygosity in outbred human populations [PDF]

Human Molecular Genetics, 2006
Long tracts of consecutive homozygous single nucleotide polymorphisms (SNPs) can arise in the genome through a number of mechanisms. These include inbreeding in which an individual inherits chromosomal segments that are identical by descent from each parent. However, recombination and other processes break up chromosomal segments over generations.
Gibson, Jane, Morton, Newton E., Collins, Andrew   +2 more
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Genomic growth curves of an outbred pig population [PDF]

Genetics and Molecular Biology, 2013
In the current post-genomic era, the genetic basis of pig growth can be understood by assessing SNP marker effects and genomic breeding values (GEBV) based on estimates of these growth curve parameters as phenotypes. Although various statistical methods, such as random regression (RR-BLUP) and Bayesian LASSO (BL), have been applied to genomic selection
Silva, Fabyano Fonseca e, Resende, Marcos Deon V. de, Rocha, Gilson Silvério, Duarte, Darlene Ana S., Lopes, Paulo Sávio, Brustolini, Otávio J.B., Thus, Sander, Viana, José Marcelo S., Guimarães, Simone E.F.   +8 more
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A Nomenclatural System for Outbred Animals,,

ILAR Journal, 2021
EDITOR’S NOTE With the possible exception of inbred mice, the identification of laboratory animals has been in a state of anarchy until very recently. In a letter to the editor of LABORATORY ANIMAL CARE (19: 121–123, 1969), Mr. Samuel Poiley outlined the general principles of a system of nomenclature being developed by the Committee on ...
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Homozygosity mapping in outbred families with mental retardation [PDF]

European Journal of Human Genetics, 2011
Autosomal recessive mental retardation (AR-MR) may account for up to 25% of genetic mental retardation (MR). So far, mapping of AR-MR genes in consanguineous families has resulted in six nonsyndromic genes, whereas more than 2000 genes might contribute to AR-MR.
Schuurs-Hoeijmakers, J.H.M., Hehir, J.Y., Pfundt, R., Bon, B.W.M. van, Leeuw, N. de, Kleefstra, T., Willemsen, M.A.A.P., Geurts van Kessel, A.H.M., Brunner, H.G., Veltman, J.A., Bokhoven, J.H.L.M. van, Brouwer, A.P.M. de, Vries, L.B.A. de   +12 more
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Determination of biological activity of gonadotrophins in inbred and outbred animals. Part 1: Determination of biological activity of follicle-stimulating hormone

Регуляторные исследования и экспертиза лекарственных средств, 2023
Scientific relevance. The biological activity of medicinal products may vary depending on the method of production (i.e. biological or recombinant products).
T. A. Batuashvili, E. O. Chechetova, P. V. Shadrin, N. P. Neugodova   +3 more
doaj   +1 more source

Inbreeding Alters the Chemical Phenotype and Mating Behavior of a Beetle

Frontiers in Ecology and Evolution, 2018
Mating between closely related individuals is often associated with fitness declines. However, less is known about consequences of inbreeding for (sexual) chemical signaling traits and for mate choice and acceptance.
Thorben Müller, Laura Lachenicht, Caroline Müller   +2 more
doaj   +1 more source

Inbreeding depression in Solanum carolinense (Solanaceae) under field conditions and implications for mating system evolution. [PDF]

PLoS ONE, 2011
The clonal weed Solanum carolinense exhibits plasticity in the strength of its self-incompatibility (SI) system and suffers low levels of inbreeding depression (δ) in the greenhouse. We planted one inbred and one outbred plant from each of eight maternal
Rupesh R Kariyat, Sarah R Scanlon, Mark C Mescher, Consuelo M De Moraes, Andrew G Stephenson   +4 more
doaj   +1 more source

Females prefer the scent of outbred males: good-genes-as-heterozygosity?

BMC Evolutionary Biology, 2009
Background There is increasing interest to determine the relative importance of non-additive genetic benefits as opposed to additive ones for the evolution of mating preferences and maintenance of genetic variation in sexual ornaments. The 'good-genes-as-
Thoß Michaela, Stundner Gloria, Ilmonen Petteri, Penn Dustin J   +3 more
doaj   +1 more source

Experimental Induction of Lyme Arthritis in Outbred Mice [PDF]

Microbiology and Immunology, 1994
AbstractOutbred ddY mice inoculated with live cells ofBorrelia burgdorferistrain 297 into hind footpad displayed swelling of the footpad at days 7 to 11 after inoculation. Marked neutrophilic infiltration was observed in the subcutaneous tissue and the part of bone tissue which was partially destroyed, and synovial layer of articular capsule was ...
T, Masuzawa, T, Kurita, H, Kawabata, H, Suzuki, Y, Yanagihara   +4 more
openaire   +2 more sources