Results 81 to 90 of about 1,496,473 (269)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Assuring quality health care outcomes: lessons learned from car dealers?
Patient Related Outcome Measures, 2017 Joel E Dimsdale Department of Psychiatry, University of California, San Diego, CA, USA Abstract: Health care systems want quality but struggle to find the right tools because, typically, they track quality in only one or two ways.
Dimsdale JE
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Developing a handheld record for patients with cystic fibrosis
Patient Related Outcome Measures, 2015 Omendra Narayan,1 Siobhan Davies,1 Carly Tibbins,2 JH Martyn Rees,3 Warren Lenney,1,4 Francis J Gilchrist1,4 1Academic Department of Child Health, Royal Stoke University Hospital, Stoke-on-Trent, 2West Midlands Medicines for Children Research Network ...
Narayan O +5 more
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Enablers of and Barriers to Effective Diabetes Self-Care in Iran: A Qualitative Study
Patient Related Outcome Measures, 2020 Davood Robat Sarpooshi,1 Ali Taghipour,2 Mehrsadat Mahdizadeh,3 Nooshin Peyman3 1Department of Health Education and Health Promotion, Social Determinants of Health Research Center, Student Research Committee, School of Health, Mashhad University of ...
Robat Sarpooshi D +3 more
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Patient Related Outcome Measures, 2019 Andy Ho1,2, Christa Purdie1,2, Oren Tirosh,3 Phong Tran3,41Faculty of Medicine, University of Melbourne, Melbourne, VIC, Australia; 2Western Clinical School, Western Health, Footscray, Melbourne, VIC, Australia; 3Department of Orthopaedic Surgery ...
Ho A, Purdie C, Tirosh O, Tran P
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FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
A systematic review of patient-reported measures of burden of treatment in three chronic diseases
Patient Related Outcome Measures, 2013 David T Eton,1 Tarig A Elraiyah,2 Kathleen J Yost,3 Jennifer L Ridgeway,1 Anna Johnson,2 Jason S Egginton,1 Rebecca J Mullan,4 Mohammad Hassan Murad,2 Patricia J Erwin,2 Victor M Montori1,2 1Division of Heath Care Policy and Research, Department of ...
Eton DT +9 more
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