Results 71 to 80 of about 1,561,444 (269)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Ida Babakhanyan,1,2 Benjamin S McKenna,2 Kaitlin B Casaletto,3 Cindy J Nowinski,4 Robert K Heaton2 1Defense and Veteran’s Brain Injury Center, Camp Pendleton, 2Department of Psychiatry, University of California, San Diego, La Jolla, 3Department of ...
Babakhanyan I +4 more
doaj
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Anil Gumber, Bhanu Ramaswamy, Oranuch Thongchundee Faculty of Health and Wellbeing, Sheffield Hallam University, Sheffield S10 2BP, UKCorrespondence: Anil GumberFaculty of Health and Wellbeing, Sheffield Hallam University, Collegiate Hall, Sheffield S10 ...
Gumber A, Ramaswamy B, Thongchundee O
doaj
Carla M Bastemeijer,1 Hileen Boosman,2 Linda Zandbelt,3 Reinier Timman,4 Dolf de Boer,5 Jan A Hazelzet1 1Department of Public Health, Erasmus University Medical Center, Rotterdam, the Netherlands; 2Department of Quality & Patient Safety, Leiden ...
Bastemeijer CM +5 more
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Evalill Nilsson1, Margareta Kristenson21Department of Social and Welfare Studies, Linköping University, Linköping, Sweden; 2Department of Medicine and Health, Division of Community Medicine/Social Medicine and Public Health Sciences ...
Evalill Nilsson, Margareta Kristenson
doaj
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
On the Objectivity of Measurement Outcomes [PDF]
28 pages, 4 figures; version accepted for publication in the British Journal for Philosophy of ...
openaire +2 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source

