Results 71 to 80 of about 1,496,473 (269)

Impact of Stigma on People Living with Chronic Hepatitis B

Patient Related Outcome Measures, 2020
Jayne Smith-Palmer,1 Karin Cerri,2 Urbano Sbarigia,2 Eric KH Chan,3 Richard F Pollock,1 William J Valentine,1 Kristien Bonroy2 1Ossian Health Economics and Communications, Basel, Switzerland; 2Janssen Pharmaceutica NV, Beerse, Belgium; 3Janssen Global ...
Smith-Palmer J, Cerri K, Sbarigia U, Chan EKH, Pollock RF, Valentine WJ, Bonroy K   +6 more
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Validity of Current Assessment Tools Aiming to Measure the Affective Component of Pain: A Systematic Review

Patient Related Outcome Measures, 2021
Anders Heiberg Agerbeck,1– 3 Frederik Handberg Juul Martiny,1,2 Christian Patrick Jauernik,1,2,* Karin Due Bruun,3,4,* Or Joseph Rahbek,1,2,* Kristine H Bissenbakker,1,2 John Brodersen1,2 1The Section of General Practice and Research Unit for
Heiberg Agerbeck A, Martiny FHJ, Jauernik CP, Due Bruun K, Rahbek OJ, Bissenbakker KH, Brodersen J   +6 more
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

A qualitative assessment of an online support community for ovarian cancer patients

Patient Related Outcome Measures, 2012
Preetinder Singh Gill, Billy WhisnantCollege of Technology, Eastern Michigan University, Ypsilanti, MI, USABackground: A diagnosis of ovarian cancer can have detrimental effects on afflicted patients and their families.
Gill PS, Whisnant B
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Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Correlations between patient-reported outcomes and self-reported characteristics in adults with hemophilia B and caregivers of children with hemophilia B: analysis of the B-HERO-S study

Patient Related Outcome Measures, 2019
Tyler W Buckner,1 Robert Sidonio Jr,2 Michelle Witkop,3 Christine Guelcher,4 Susan Cutter,5 Neeraj N Iyer,6 David L Cooper6 1Hemophilia and Thrombosis Center, University of Colorado School of Medicine, Aurora, CO, USA; 2Department of Pediatrics, Aflac ...
Buckner TW, Sidonio Jr R, Witkop M, Guelcher C, Cutter S, Iyer NN, Cooper DL   +6 more
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Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Understanding and optimizing health-related quality of life and physical functional capacity in idiopathic pulmonary fibrosis

Patient Related Outcome Measures, 2016
Amy L Olson, Kevin K Brown, Jeffrey J SwigrisDepartment of Medicine Division of Pulmonary Medicine, Interstitial Lung Disease Program and Autoimmune Lung Center, National Jewish Health, Denver, CO, USA Abstract: Idiopathic pulmonary fibrosis (IPF) is a ...
Olson AL, Brown KK, Swigris JJ
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