Results 91 to 100 of about 1,496,473 (269)

Outcome measures for rheumatologists [PDF]

Rheumatology, 2003
V V, Kaushik, V E, Abernethy, M P, Lynch, J K, Dawson   +3 more
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Administering the Routine Activities domain of the Oxford Participation and Activities Questionnaire as a stand-alone scale: the Oxford Routine Activities Measure

Patient Related Outcome Measures, 2018
David Morley, Sarah Dummett, Laura Kelly, Crispin Jenkinson Nuffield Department of Population Health, University of Oxford, Oxford, UK Background: The recently validated Oxford Participation and Activities Questionnaire (­Ox-PAQ) is a 23-item patient-
Morley D, Dummett S, Kelly L, Jenkinson C   +3 more
doaj  

Can Patient Reported Outcomes (PROs) from Population Surveys Provide Accurate Estimates of Pre-Admission Health Status of Emergency Hospital Admissions?

Patient Related Outcome Measures, 2020
Esther Kwong,1 Gary Abel,2 Nick Black1 1Department of Health Services Research & Policy, London School of Hygiene and Tropical Medicine, London WC1H 9SH, UK; 2College of Medicine and Health, University of Exeter, Exeter EX4 4PY, UKCorrespondence ...
Kwong E, Abel G, Black N
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

How do disease perception, treatment features, and dermatologist–patient relationship impact on patients assuming topical treatment? An Italian survey

Patient Related Outcome Measures, 2015
Anna Graziella Burroni,1 Mariella Fassino,2 Antonio Torti,3 Elena Visentin4 1IRCCS University Hospital San Martino, IST National Institute for Cancer Research, Genoa, Italy; 2Department of Psychology, Specialization School in Clinical Psychology ...
Burroni AG, Fassino M, Torti A, Visentin E   +3 more
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Hablamos juntos (together we speak): a brief patient-reported measure of the quality of interpretation

Patient Related Outcome Measures, 2014
Efrain Talamantes,1 Gerardo Moreno,2 Lourdes R Guerrero,3 Carol M Mangione,3,4 Leo S Morales5,6 1US Department of Veterans Affairs and Division of General Internal Medicine, Division of General Internal Medicine and Health Services Research, University ...
Talamantes E, Moreno G, Guerrero LR, Mangione CM, Morales LS   +4 more
doaj  

Measuring Outcome [PDF]

Journal of the Royal Society of Medicine, 1985
openaire   +2 more sources