Results 111 to 120 of about 14,326,866 (362)

A systematic review to investigate outcome tools currently in use for those with hand burns, and mapping psychometric properties of outcome measures

open access: yes, 2020
Background: Severe burn injuries to the hand impact multiple domains of function and participation. Measurement of outcomes after hand burn injuries is multifaceted and is influenced by several variables.
Gustafsson, Louise   +5 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Health-related quality of life in patients with iron deficiency anemia: impact of treatment with intravenous iron

open access: yesPatient Related Outcome Measures, 2018
William E Strauss,1 Michael Auerbach2 1AMAG Pharmaceuticals, Inc., Waltham, MA, USA; 2Auerbach Hematology and Oncology, Baltimore, MD, USA Abstract: Most physicians appear to be aware of the health consequences of advanced anemia, especially in the acute
Strauss WE, Auerbach M
doaj  

Content Validation of the ATTR Amyloidosis Patient Symptom Survey: Findings from Patient and Clinician Cognitive Debriefing Interviews

open access: yesPatient Related Outcome Measures, 2020
Avery A Rizio,1 Lynne E Broderick,1 Michelle K White,1 Tiffany P Quock2 1Optum Life Sciences, Patient Insights, Johnston, RI, USA; 2Prothena Biosciences Inc, South San Francisco, CA, USACorrespondence: Avery A RizioOptum Life Sciences, Patient Insights ...
Rizio AA   +3 more
doaj  

A prospectus for mental health outcome measures

open access: yes, 2001
A prospectus for mental health outcome ...
TANSELLA, Michele, THORNICROFT G.
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Patient considerations in the management of gout and role of combination treatment with lesinurad

open access: yesPatient Related Outcome Measures, 2018
Liza W Claus, Joseph J Saseen Department of Clinical Pharmacy, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO, USA Abstract: Gouty arthritis is one of the most common rheumatic diseases, and the prevalence ...
Claus LW, Saseen JJ
doaj  

The Digital Outcome Measure

open access: yesDigital Biomarkers, 2018
Improving clinical outcomes remains the gold standard in advancing healthcare. Focusing on outcomes holds the potential to unite all clinical stakeholders including payers, industry, providers, and patients. Yet, the dominant ways in which outcomes are captured, provider-collected or patient-reported, have significant limitations. The emerging field of
Adam B, Cohen, Simon C, Mathews
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Patient-reported outcome measures in arthroplasty registries

open access: yes, 2017
The International Society of Arthroplasty Registries (ISAR) Steering Committee established the Patient-Reported Outcome Measures (PROMs) Working Group to convene, evaluate, and advise on best practices in the selection, administration, and interpretation
Patient-Reported Outcome Measures Working Group of the International Society of Arthroplasty Registries   +12 more
core   +1 more source

Home - About - Disclaimer - Privacy