Results 131 to 140 of about 3,411,169 (350)
Conserved Omp85 lid-lock structure and substrate recognition in FhaC [PDF]
, 2015 Omp85 proteins mediate translocation of polypeptide substrates across and into cellular membranes. They share a common architecture comprising substrate-interacting POTRA domains, a C-terminal 16-stranded β-barrel pore and two signature motifs located on
Delattre, Anne-Sophie +7 more
core +1 more source
The Power of Asymmetry: Architecture and Assembly of the Gram-Negative Outer Membrane Lipid Bilayer
Annual Review of Microbiology, 2016 Determining the chemical composition of biological materials is paramount to the study of natural phenomena. Here, we describe the composition of model gram-negative outer membranes, focusing on the predominant assembly, an asymmetrical bilayer of lipid ...
M. Chevrette +9 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
The outer limiting membrane (OLM) revisited: clinical implications
Clinical Ophthalmology, 2010 S Omri1,2,3, B Omri1,2,3, M Savoldelli1,2,3,4, L Jonet1,2,3, B Thillaye-Goldenberg1,2,3, G Thuret5, P Gain5, J C Jeanny1,2,3, P Crisanti1,2,3, Francine Behar-Cohen1,2,3,41INSERM, U872 Physiopathology of ocular diseases: Therapeutic innovations, Paris ...
S Omri, B Omri, M Savoldelli, et al
doaj
Functional Versatility of Vibrio cholerae Outer Membrane Proteins
Applied MicrobiologyA key feature that differentiates Gram-positive and Gram-negative bacteria is the outer membrane, an asymmetric membrane composed of lipopolysaccharides, phospholipids, lipoproteins and integral proteins, including the outer-membrane proteins (OMPs).
Annabelle Mathieu-Denoncourt +1 more
doaj +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Transport of proteins across mitochondrial membranes [PDF]
, 1994 The vast majority of proteins comprising the mitochondrion are encoded by nuclear genes, synthesized on ribosomes in the cytosol, and translocated into the various mitochondrial subcompartments. During this process proteins must cross the lipid membranes
Neupert, Walter
core +1 more source
Lipopolysaccharide transport and assembly at the outer membrane: the PEZ model
Nature Reviews Microbiology, 2016 Gram-negative bacteria have a double-membrane cellular envelope that enables them to colonize harsh environments and prevents the entry of many clinically available antibiotics.
Suguru Okuda +4 more
semanticscholar +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
LPS Remodeling Triggers Formation of Outer Membrane Vesicles in Salmonella
mBio, 2016 Outer membrane vesicles (OMV) are proposed to mediate multiple functions during pathogenesis and symbiosis. However, the mechanisms responsible for OMV formation remain poorly understood.
W. Elhenawy +7 more
semanticscholar +1 more source