Results 71 to 80 of about 3,411,169 (350)
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Helicobacter pylori Outer Membrane Protein-Related Pathogenesis
Toxins, 2017 Helicobacter pylori colonizes the human stomach and induces inflammation, and in some cases persistent infection can result in gastric cancer. Attachment to the gastric mucosa is the first step in establishing bacterial colonization, and outer membrane ...
Yuichi Matsuo +2 more
doaj +1 more source
A Msp1-containing complex removes orphaned proteins in the mitochondrial outer membrane of T. brucei
Life Science Alliance, 2023 Disruption of mitochondrial outer membrane protein biogenesis triggers a pathway leading to proteasomal degradation of orphan outer membrane proteins mediated by Msp1 and three interacting proteins.
Markus Gerber +7 more
doaj +1 more source
Bioengineering bacterial outer membrane vesicles as vaccine platform.
Biotechnology Advances, 2017 Outer membrane vesicles (OMVs) are naturally non-replicating, highly immunogenic spherical nanoparticles derived from Gram-negative bacteria. OMVs from pathogenic bacteria have been successfully used as vaccines against bacterial meningitis and sepsis ...
Matthias J. H. Gerritzen +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Imaging and 3D reconstruction of membrane protein complexes by cryo-electron microscopy and single particle analysis [PDF]
, 2006 Cryo-electron microscopy (cryo-EM) in combination with single particle image processing and volume reconstruction is a powerful technology to obtain medium-resolution structures of large protein complexes, which are extremely difficult to crystallize and ...
Gregorini, Marco
core +1 more source
Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis
PLoS Pathogens, 2018 Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhoea by evading innate immunity. Colonizing the mucosa of the reproductive tract depends on the bacterial outer membrane porin, PorB, which is essential for ion and nutrient uptake. PorB
P. Deo +12 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
BMC Genomics, 2009 Background Chlamydiae are obligate intracellular bacteria comprising some of the most important bacterial pathogens of animals and humans. Although chlamydial outer membrane proteins play a key role for attachment to and entry into host cells, only few ...
Myers Garry +5 more
doaj +1 more source
A bacterial membrane sculpting protein with BAR domain-like activity
eLife, 2021 Bin/Amphiphysin/RVS (BAR) domain proteins belong to a superfamily of coiled-coil proteins influencing membrane curvature in eukaryotes and are associated with vesicle biogenesis, vesicle-mediated protein trafficking, and intracellular signaling. Here, we
Daniel A Phillips +13 more
doaj +1 more source