Results 241 to 250 of about 3,299,410 (293)

The Interplay of Curvature, Geometry, and Topology Shapes Tissue Organisation in Epithelial Shells

Advanced Science, EarlyView.
Purely geometric 3D Voronoi models predict the organisation of epithelial shells. The interplay of curvature, geometry, and topology enriches the number of pentagons in shells with lower number of cells. Small MDCK cysts and Mouse embryos match the top polygonal configurations in a compactness‐based ranking derived from the Voronoi model. In conclusion,
Laura Morato, Jesús A. Andrés‐San Román, Juan Garrido‐García, Carmen Gordillo‐Vázquez, Ana M. Palacios, Elisabeth Lidueña‐Fernández, Katie McDole, Pedro Gómez‐Gálvez, Valentina Annese, Luis M. Escudero   +9 more
wiley   +1 more source

Oligosaccharides With Defined Glycosidic Bonds Shape Gut Microbial Succession and Metabolism Via Bond‐Specific Microbial Responders

Advanced Science, EarlyView.
Oligosaccharides with defined glycosidic bonds drive divergent gut microbial succession and shape unique metabolic profiles. Absolute time‐series profiling with Bayesian generalized Lotka–Volterra modeling identifies bond‐specific microbial responders, while monoculture validation and metaproteomics reveal linkage‐matched transport and cleavage modules.
Xiaoxuan Lu, Jiaqi Zou, Geng Han, Mengyao Zhao, Ting Luo, Xiangru Feng, Liangliang Zhu, Yijia Chen, Xiaoguo Ji, Jiayang Jin, Liming Zhao   +10 more
wiley   +1 more source

Deubiquitination of Vangl by USP6 and USP32 Regulates Planar Cell Polarity Signaling

Advanced Science, EarlyView.
Compartment‐specific deubiquitination controls Vangl dosage and planar cell polarity signaling. USP6 and USP32 regulate distinct subcellular pools of Vangl by removing distinct ubiquitin modifications from Vangl proteins. This regulatory mechanism safeguards PCP‐dependent embryonic morphogenesis, while aberrant USP32‐dependent stabilization of VANGL ...
Fangzi Zha, Di Feng, Ziru Xue, Zhiying Liu, Xiaochen Lin, Zhe Wang, Ling Xu, Jasper Fuk Woo Chan, Martin Cheung, Michael Shing Yan Huen, Yusong Guo, Kui Ming Chan, Yun Liu, Bo Gao   +13 more
wiley   +1 more source

Characterisation of Putative Outer Membrane Proteins from <i>Leptospira borgpetersenii</i> Serovar Hardjo-Bovis Identifies Novel Adhesins and Diversity in Adhesion across Genomospecies Orthologs. [PDF]

Microorganisms
Kamaruzaman INA, Staton GJ, Ainsworth S, Carter SD, Evans NJ.   +4 more
europepmc   +1 more source

Sequence variability of BamA and FadL candidate vaccinogens suggests divergent evolutionary paths of Treponema pallidum outer membrane proteins

Bettin EB, Aghakhanian F, Hennelly CM, Chen W, Davenport TC, Hackl ST, Grassmann AA, Vargas-Cely F, Silva S, García-Luna JA, Ramirez LG, Jiang Y, Yang L, Zheng H, Yang B, Pospíšilová P, Šmajs D, Matoga MM, Hoffman IF, López-Medina E, Nieselt K, Moody MA, Seña AC, Salazar JC, Parr JB, Caimano MJ, Hawley KL, Radolf JD.   +27 more
europepmc   +1 more source

Simulations of bacterial outer membrane proteins: Towards an e-outer membrane

, 2016
Baaden, M, Sansom, M, Bond, P, Cox, K, Deol, S, Faraldo-Gomez, J, Meier, C   +6 more
openaire   +1 more source

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Outer membrane protein evolution

Current Opinion in Structural Biology, 2021
Outer membrane proteins have remarkably homogeneous structure. They are all up down β-barrels. Up down barrels themselves are composed of repeated sets of β-hairpins. The consistency of the usage of the β-hairpin throughout the outer membrane milieu allows for interrogation of the evolution of these repetitive structures.
Rik, Dhar, Joanna Sg, Slusky
openaire   +2 more sources

Biogenesis of Mitochondrial Outer Membrane Proteins

Biochimica Et Biophysica Acta - Molecular Cell Research, 2009
Mitochondria are surrounded by two distinct membranes: the outer and the inner membrane. The mitochondrial outer membrane mediates numerous interactions between the mitochondrial metabolic and genetic systems and the rest of the eukaryotic cell. Proteins of this membrane are nuclear-encoded and synthesized as precursor proteins in the cytosol. They are
Doron Rapaport
exaly   +3 more sources

Insights Into Outer Membrane Protein Crystallization [PDF]

Molecular Membrane Biology, 2008
Outer membrane proteins are structurally distinct from those that reside in the inner membrane and play important roles in bacterial pathogenicity and human metabolism. X-ray crystallography studies on >40 different outer membrane proteins have revealed that the transmembrane portion of these proteins can be constructed from either beta-sheets or less ...
Simon Newstead, Liz Carpenter, So Iwata
exaly   +4 more sources