Results 51 to 60 of about 3,299,410 (293)

Protein-induced modulation of chloroplast membrane morphology [PDF]

, 2012
Organelles are surrounded by membranes with a distinct lipid and protein composition. While it is well established that lipids affect protein functioning and vice versa, it has been only recently suggested that elevated membrane protein concentrations ...
Maik S Sommer, Enrico eSchleiff, Machettira, Anu Bheemaiah, Anu B. Machettira, Englich, Gisela, Anu B Machettira, Benjamin LM Weis, Lucia E. Groß, Giesela eEnglich, Enrico Schleiff, Weis, Benjamin L., Gisela Englich, Lucia E Groß, Schleiff, Enrico, Königer, Martina, Martina eKöniger, Bodo Tillmann, Groß, Lucia E., Sommer, Maik Sascha, Benjamin L. Weis, Bodo eTillmann, Martina Königer, Tillmann, Bodo, Maik S. Sommer   +23 more
core   +1 more source

Import and Insertion of Proteins into the Mitochondrial Outer Membrane [PDF]

European Journal of Biochemistry, 1995
Nuclear‐encoded proteins destined for insertion into the mitochondrial outer membrane, follow the same general pathway for import as proteins that are translocated to interior compartments within the organelle. This observation is true both for β‐barrel‐type proteins and for proteins that contain hydrophobic α‐helical transmembrane segments.
Shore, G. C., McBride, H. M., Millar, D. G., Steenaart, N. A E, Nguyen, M.   +4 more
openaire   +2 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Cross-species chimeras reveal BamA POTRA and β-barrel domains must be fine-tuned for efficient OMP insertion [PDF]

, 2015
BAM is a conserved molecular machine, the central component of which is BamA. Orthologues of BamA are found in all Gram-negative bacteria, chloroplasts and mitochondria where it is required for the folding and insertion of β-barrel containing integral ...
Jeeves, Mark, Mason, Jessica L, Knowles, Timothy J., Rossiter, Amanda E, Rossiter, Amanda E.; id_orcid, Browning, Douglas F., Bavro, Vassiliy N., Henderson, Ian R., Cunningham, Adam F., Overduin, Michael, Sevastsyanovich, Yanina R., Rossiter, Amanda E., Donald, James W., Browning, Douglas F, Wells, Timothy J, Henderson, Ian R, Knowles, Timothy J.; id_orcid, Wells, Timothy J., Palmer, Tracy, Knowles, Timothy J, Sevastsyanovich, Yanina R, Cunningham, Adam F, Mason, Jessica L., Bavro, Vassiliy N, Donald, James W   +24 more
core   +1 more source

Anti-outer Membrane Vesicle Antibodies Increase Antibiotic Sensitivity of Pan-Drug-Resistant Acinetobacter baumannii

Frontiers in Microbiology, 2019
Acinetobacter baumannii often causes serious nosocomial infections. Because of its serious drug resistance problems, complex drug resistance mechanism, and rapid adaptation to antibiotics, it often shows pan-drug resistance and high fatality rates, which
Weiwei Huang, Qishu Zhang, Weiran Li, Yongjun Chen, Congyan Shu, Qingrong Li, Jingxian Zhou, Chao Ye, Hongmei Bai, Wenjia Sun, Xu Yang, Yanbing Ma   +11 more
doaj   +1 more source

Skp is a multivalent chaperone of outer-membrane proteins [PDF]

Nature Structural & Molecular Biology, 2016
The trimeric chaperone Skp sequesters outer-membrane proteins (OMPs) within a hydrophobic cage, thereby preventing their aggregation during transport across the periplasm in Gram-negative bacteria. Here, we studied the interaction between Escherichia coli Skp and five OMPs of varying size.
Schiffrin, B, Calabrese, AN, Devine, PWA, Harris, SA, Ashcroft, AE, Brockwell, DJ, Radford, SE   +6 more
openaire   +3 more sources

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Characterization of the protein import apparatus in isolated outer envelopes of chloroplasts [PDF]

, 1991
Isolated outer envelope membrane from pea (Pisum sativum L.) chloroplasts can be used in vitro to study binding and partial translocation of precursor proteins destined for the inside of the organelle.
Soll, Jürgen, Waegemann, Karin
core   +1 more source

Import pathways of precursor proteins into mitochondria [PDF]

, 1988
The precursor of porin, a mitochondrial outer membrane protein, competes for the import of precursors destined for the three other mitochondrial compartments, including the Fe/S protein of the bc1- complex (intermembrane space), the ADP/ATP carrier ...
Pfaller, Rupert, Pfanner, Nikolaus, Steger, Heinrich F., Rassow, Joachim, Neupert, Walter   +4 more
core   +1 more source

Characterization of Helicobacter pylori aggregation reveals a requirement for both AlpA and AlpB

Journal of Bacteriology
Helicobacter pylori is a gram-negative human pathogen that colonizes the stomach and is a major risk factor for gastric ulcers and cancer. A common but poorly understood characteristic of H. pylori is its propensity to aggregate in liquid culture.
Alexander Solov, Xiaolin Liu, Yasveck Duran-Ramirez, Corey Witt, Karen M. Ottemann   +4 more
doaj   +1 more source