Results 71 to 80 of about 3,299,410 (293)

A morphological view on mitochondrial protein targeting [PDF]

, 1994
Mitochondrial protein targeting includes both intramitochondrial sorting of proteins encoded by the organellar genome and import and subsequent sorting of nuclear encoded precursor proteins. Only a few proteins are encoded by the mitochondrial genome and
Ida J. van der Klei, Walter Neupert, Neupert, Walter, Marten Veenhuis, Veenhuis, Marten, Klei, Ida J. van der   +5 more
core   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

The invariant phenylalanine of precursor proteins discloses the importance of Omp85 for protein translocation into cyanelles [PDF]

, 2007
Background Today it is widely accepted that plastids are of cyanobacterial origin. During their evolutionary integration into the metabolic and regulatory networks of the host cell the engulfed cyanobacteria lost their independency.
Schleiff Enrico, Roman Martin, Martin, Roman, Steiner Jürgen M, Steiner, Jürgen M., Loeffelhardt, Wolfgang, Löffelhardt Wolfgang, Steiner, Juergen M., Wunder Tobias, Tobias Wunder, Enrico Schleiff, Jürgen M Steiner, Martin Roman, Wunder, Tobias, Schleiff, Enrico, Löffelhardt, Wolfgang, Wolfgang Löffelhardt   +16 more
core   +1 more source

Cross Reaction among Antibody Pili sub unit Hemagglutinin Proteins and Outer Membrane sub unit Hemagglutinin Proteins of Shigella flexneri

Journal of Tropical Life Science, 2017
Shigella  flexneri is the most common causal agent of shigellosis. Its pili are composed of pili protein subunits. Adhesion molecules can be found on the pili and outer membrane proteins (Omp).
Avin Ainur Fitrianingsih, Lailia Nur Rachma, Alvi Milliana, Tinny Endang Hernowati, Aulanni'am Aulanni'am, Sanarto Santoso, Sumarno Reto Prawiro   +6 more
doaj   +1 more source

The expression of outer membrane proteins for crystallization

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2003
The production of sufficient amounts of chemically and conformationally homogenous protein is a major requirement for successful crystallization and structure determination. With membrane proteins, this constitutes a particular problem because the membrane volume is limited and the organisms are usually very sensitive to changes in membrane properties ...
Bannwarth, Michael, Schulz, Georg E.
openaire   +3 more sources

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Preparation of Bacterial Outer Membrane Vesicles for Characterisation of Periplasmic Proteins in Their Native Environment

Bio-Protocol, 2020
Bacterial outer membrane vesicles (OMVs) are naturally formed by budding from the outer membrane of Gram-negative bacteria. OMVs consist of a lipid bilayer identical in composition to the original outer membrane and contain periplasmic content within ...
Johannes Thoma, Björn Burmann
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A mechanism of protein localization : the signal hypothesis and bacteria [PDF]

, 1980
We are studying the molecular mechanism of cellular protein localization. The availability of genetic techniques, such as gene fusion in Escherichia coli, has made this problem particularly amenable to study in this prokaryote.
Hall, M. N., Silhavy, T. J., Emr, S. D., T J Silhavy, S D Emr, M N Hall   +5 more
core   +1 more source