Results 231 to 240 of about 84,904 (290)

Intraperitoneal Injection of the Porphyromonas gingivalis Outer Membrane Vesicle (OMV) Stimulated Expressions of Neuroinflammatory Markers and Histopathological Changes in the Brains of Adult Zebrafish. [PDF]

Int J Mol Sci
Adewoyin M, Hamarsha A, Akinsola R, Teoh SL, Azmai MNA, Abu Bakar N, Nasruddin NS.   +6 more
europepmc   +1 more source

Uniform Microscale Thermoresponsive Liposomes for Controlled Release Above Body Temperature

Small, EarlyView.
Uniform thermoresponsive liposomes are generated using a scalable double‐emulsion microfluidic approach coupled with accelerated solvent extraction. The resulting liposomes remain stable at physiological temperature but undergo abrupt rupture and cargo release at 41°C–45°C, providing a versatile platform for thermally triggered controlled release in ...
S. Morteza Mousavi, Yang Zhang, Elvis Pandzic, David W. Inglis, Megan S. Lord, Robert A. Taylor, Ming Li   +6 more
wiley   +1 more source

Pneumonic Plague Protection Induced by a Monophosphoryl Lipid A Decorated Yersinia Outer-Membrane-Vesicle Vaccine. [PDF]

Small
Majumder S, Das S, Li P, Yang N, Dellario H, Sui H, Guan Z, Sun W.   +7 more
europepmc   +1 more source

Cancer Vaccine Development: Toward Artificial Intelligence‐Assisted Personalized Cell Membrane Nanovaccine

Small, EarlyView.
Cancer nanovaccines have emerged as promising alternatives to conventional cancer vaccines, which have shown limited clinical efficacy. In particular, cell membrane nanoparticle‐based nanovaccines can offer high biocompatibility and immunogenicity while preserving tumor antigens, including antigen repertoires.
Munsik Kim, Ilkoo Noh
wiley   +1 more source

A major role for intestinal epithelial nucleotide oligomerization domain (NOD) protein NOD1 in mediating host bactericidal activity against Campylobacter jejuni [PDF]

, 2007
Wren, B, Elmi, A, Bajaj-Elliott, M, Wren, BW, Nunez, G, Dorrell, N, Klein, NJ, Lindley, K, Zilbauer, M, Klein, N   +9 more
core  

Qilian Jiechang Ning Alleviates TNBS-Induced Ulcerative Colitis in Mice and Segatella copri Outer Membrane Vesicle-Triggered Inflammation in Colon Epithelial Cells via the Caspase-1/11-GSDMD Pathways. [PDF]

J Innate Immun
Hu J, Niu J, Jiang S, Wu Y.
europepmc   +1 more source

Polymersome‐Enabled Multimodal Delivery of Tobramycin and Doripenem for Targeted Eradication of Pseudomonas aeruginosa Biofilms in Chronic Rhinosinusitis

Small, EarlyView.
Schematic representation of diffusion‐based versus pH‐triggered drug release within a bacterial biofilm. In diffusion‐based systems, drug cargo is gradually released independent of local pH, resulting in rapid burst release and reduced sustained concentrations.
Amalie Kjær Andresen, Matteo Tollemeto, Alexander B. Cook, Claus Sternberg, Yudong Li, Claus Moser, Lars Jelsbak, Jan C. M. Van Hest, Anja Boisen, Line Hagner Nielsen   +9 more
wiley   +1 more source

Active pH Modulation by Proton Channel‐Peptide Nucleic Acid Complex for Effective siRNA Endosomal Escape

Small, EarlyView.
A bioinspired siRNA nanocarrier is engineered by integrating an influenza A M2 proton channel with siRNA through a peptide nucleic acid linker on liposome surfaces. Active proton transport amplifies osmotic stress within endosomes, triggering membrane rupture and cytosolic release.
Seongmin Ga, Nam Hyeong Kim, Si Yeon Ryu, Kyeonghyun Kim, Eun Sung Kang, Hayeon Bae, Seungmin Ryu, Suhyeon Kim, Yeontae Jang, Bok‐Soo Lee, Jiyoung Nam, Minah Suh, Jaecheol Lee, Seung‐gu Kang, Jaekyung Hyun, Huong T. Kratochvil, Yong Ho Kim   +16 more
wiley   +1 more source

Reverse‐Engineered Lipid Nanoparticles Harness Protein Corona Formation for Cytokine Sequestration and Combination Immunomodulatory Therapy

Small, EarlyView.
Bioinspired triglyceride‐ceramide lipid nanoparticles were reverse‐engineered from cytokine‐sequestering plant‐derived nanoparticles to capture pathological inflammatory mediators through protein corona formation. Dexamethasone‐loaded TCNPs combine extracellular cytokine sequestration with intracellular immunomodulation, reducing IL‐6, TNF‐α, and NF‐κΒ
Junsik J. Sung, Gargi Yogesh Digholkar, Ryan M. Pearson   +2 more
wiley   +1 more source

Correction: Bacterial outer membrane vesicle-cancer cell hybrid membrane-coated nanoparticles for sonodynamic therapy in the treatment of breast cancer bone metastasis. [PDF]

J Nanobiotechnology
Wang J, Liang S, Chen S, Ma T, Chen M, Niu C, Leng Y, Wang L.   +7 more
europepmc   +1 more source