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Bordetella pertussis and outer membrane vesicles
Pathogens and Global Health, 2022Bordetella pertussis is the causative agent of a respiratory infection called pertussis (whooping cough) that can be fatal in newborns and infants. The pathogen produces a variety of antigenic compounds which alone or simultaneously can damage various host cells.
Çiğdem Yılmaz Çolak +1 more
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EcoSal Plus, 2005
Outer membrane vesicles (blebs) are produced by Escherichia coli , Salmonella , and all other gram-negative bacteria both in vitro and in vivo. Most of the research in the field has focused on the properties of vesicles derived from pathogenic bacteria and their interactions with eukaryotic ...
Amanda J, McBroom, Meta J, Kuehn
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Outer membrane vesicles (blebs) are produced by Escherichia coli , Salmonella , and all other gram-negative bacteria both in vitro and in vivo. Most of the research in the field has focused on the properties of vesicles derived from pathogenic bacteria and their interactions with eukaryotic ...
Amanda J, McBroom, Meta J, Kuehn
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Outer Membrane Vesicles: Biogenesis, Functions, and Issues
Microbiology and Molecular Biology Reviews, 2022This review focuses on nonlytic outer membrane vesicles (OMVs), a subtype of bacterial extracellular vesicles (BEVs) produced by Gram-negative organisms focusing on the mechanisms of their biogenesis, cargo, and function. Throughout, we highlight issues concerning the characterization of OMVs and distinguishing them from other types of BEVs.
Rokas Juodeikis, Simon R. Carding
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Biological activities of outer membrane vesicles
Canadian Journal of Microbiology, 1989Article de synthese sur les vesicules extracellulaires (vesicules de la membrane externe) des bacteries gram negatif avec mise en relief des especes bacteriennes de la cavite buccale: conditions de formation, methodes d'isolement, composition et activites biologiques (capacite de fixation, activite bacteriocine, activites enzymatiques, activite toxique,
D, Mayrand, D, Grenier
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Biopearling of Interconnected Outer Membrane Vesicle Chains by a Marine Flavobacterium [PDF]
Large surface-to-volume ratios provide optimal nutrient uptake conditions for small microorganisms in oligotrophic habitats. The surface area can be increased with appendages.
Greta Reintjes +2 more
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Neutralization of Neisseria meningitidis outer membrane vesicles
Inflammation Research, 2011We aimed to determine the neutralization of Neisseria meningitidis outer membrane vesicles (blebs) by humoral and cellular elements of whole blood.The interaction of FITC-labeled blebs with monocytes was studied by spectrofluorometry. Blebs are able to induce an oxidative burst in neutrophils, and we evaluated the inhibitory effect of plasma on this ...
András, Vida +7 more
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Biogenesis of Outer Membrane Vesicles
2012The different steps involved in the formation and release of outer membrane vesicles (OMVs) from the parent bacteria as revealed by the experimental evidence and derived models presented by different investigators are discussed. An attempt has been made to develop a unified concept of the biogenesis of OMVs released by different Gram-negative bacteria.
S. N. Chatterjee, Keya Chaudhuri
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Immune modulation by bacterial outer membrane vesicles
Nature Reviews Immunology, 2015Gram-negative bacteria shed extracellular outer membrane vesicles (OMVs) during their normal growth both in vitro and in vivo. OMVs are spherical, bilayered membrane nanostructures that contain many components found within the parent bacterium. Until recently, OMVs were dismissed as a by-product of bacterial growth; however, findings within the past ...
Maria, Kaparakis-Liaskos +1 more
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Effect of sequence variation in meningococcal PorA outer membrane protein on the effectiveness of a hexavalent PorA outer membrane vesicle vaccine in toddlers and school children [PDF]
Though meningococcal conjugate vaccines are effective against serogroup C, there is currently no vaccine solution for serogroup B disease. PorA outer membrane protein (OMP) is a potential serogroup B vaccine candidate.
Jamie Findlow +2 more
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Acinetobacter baumannii outer membrane protein a modulates the biogenesis of outer membrane vesicles
The Journal of Microbiology, 2012Acinetobacter baumannii secretes outer membrane vesicles (OMVs) during both in vitro and in vivo growth, but the biogenesis mechanism by which A. baumannii produces OMVs remains undefined. Outer membrane protein A of A. baumannii (AbOmpA) is a major protein in the outer membrane and the C-terminus of AbOmpA interacts with diaminopimelate of ...
Dong Chan, Moon +7 more
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