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The “hole” story of predatory outer-membrane vesicles

Canadian Journal of Microbiology, 2018
All Gram-negative bacteria release membrane vesicles. These vesicles contain a cargo of proteins and enzymes that include one or more autolysins. Autolysins are a group of enzymes with specificity for the different linkages within peptidoglycan sacculi that if uncontrolled cause bacteriolysis.
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Role of outer membrane vesicles of bacteria

Resonance, 2015
Outer membrane vesicles are nano-sized spheres produced predominantly by gram-negative bacteria. They play a significant role in cell-to-cell communication, virulence, nutrition and protection of the bacterial cells from various stress factors. Recent evidences also underscore their involvement in antibiotic-resistance of bacteria.
M. V. Jagannadham, M. K. Chattopadhyay
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Purification of Borrelia burgdorferi Outer Membrane Vesicles

Bacterial outer membrane vesicles (OMVs) are spherical membrane constructs shed by gram-negative bacteria. OMVs produced by the Lyme disease pathogen Borrelia burgdorferi have been identified to contain such virulence factors as OspA, OspB, OspC, and genetic material.
Hanna, Tammisto, Kati, Karvonen
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Outer Membrane Vesicles and the Biofilm Formation

2012
Plenty of outer membrane vesicles (OMVs) are often found associated with the parent bacteria forming a biofilm. The functions of these OMVs in the biofilm are discussed in this chapter. Additional genetic and other studies are required to decide the exact role of OMVs and DNA in the formation of biofilm.
S. N. Chatterjee, Keya Chaudhuri
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Exploring the proteome of meningococcal outer membrane vesicle vaccines

PROTEOMICS – Clinical Applications, 2007
AbstractNeisseria meningitidis, one of the principal causes of bacterial meningitis and septicemia, continues to present a challenge for vaccine developers. While significant progress has been made in the development and implementation of conjugate vaccines, which are based on the capsular polysaccharide of the organism, this approach has failed to ...
Jun X, Wheeler   +2 more
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Outer Membrane Vesicles as Carriers of Biomaterials

2012
During their formation the outer membrane vesicles (OMVs) entrap, utilizing some special sorting mechanism, different materials from the periplasm and/or the outer membrane of the bacterial cell for purposes favoring the parent bacteria and against the survival of other competing organisms either in vitro or in vivo.
S. N. Chatterjee, Keya Chaudhuri
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Outer membrane vesicles in "Bordetella petrii"

2013
Gram-negative Bakterien geben während ihres Wachstums spezielle Vesikel, die als Outer Membran Vesicles (OMVs) oder Membran-Vesicle-like Particles bezeichnet werden, ab. Diese Arbeit befasst sich mit den OMVs, welche vom Bakterium Bordetella petrii abgegeben werden, und zwar mit besonderem Fokus auf die Zeitspanne, in der die Partikel-Abgabe beginnt ...
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Glycoengineered Outer Membrane Vesicles as a Platform for Vaccine Development

2017
As we enter into the postantibiotic era, vaccines to prevent bacterial infections previously treatable with antibiotics are urgently needed. Most successful antibacterial vaccines are glycoconjugates, composed of cell surface carbohydrates chemically attached to a carrier protein.
Ezequiel, Valguarnera, Mario F, Feldman
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Enrichment of Outer Membrane Vesicles Shed by Legionella pneumophila

2012
The production of outer membrane vesicles (OMVs) is a widespread phenomenon employed by bacteria to secrete cell envelope components into the environment. A contribution of Legionella pneumophila OMVs to the pathogenesis of Legionnaires' disease is likely due to the high number of virulence-related proteins in the vesicles.
Jens, Jäger, Michael, Steinert
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Outer Membrane Vesicles of Bacteria

2012
S.N. Chatterjee, Keya Chaudhuri
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