Results 31 to 40 of about 284,749 (288)
Frontiers in Microbiology, 2021 Membrane vesicles (MVs) are released by various prokaryotes and play a role in the delivery of various cell-cell interaction factors. Recent studies have determined that these vesicles are capable of functioning as mediators of horizontal gene transfer ...
Sharmin Aktar +20 more
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Bacterial Outer Membrane Vesicles and Vaccine Applications [PDF]
Frontiers in Immunology, 2014 Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of meningococcal antigens or unrelated antigens incorporated into the vesicle structure.
Acevedo, Reinaldo +10 more
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Comparison of Two Different Methods for the Extraction of Outer Membrane Vesicles from the Bordetella pertussis as a Vaccine Candidate [PDF]
Archives of Razi Institute, 2021 Despite the availability of a vaccine, pertussis is still a worldwide health problem. Outer membrane vesicles (OMVs) in gram-negative bacteria can stimulate the immune system due to several outer membrane proteins and are very good candidates in vaccine ...
M. S Soltani +4 more
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Outer Membrane Vesicles: An Emerging Vaccine Platform
Vaccines, 2022 Vaccine adjuvants are substances that improve the immune capacity of a recombinant vaccine to a great extent and have been in use since the early 1900s; they are primarily short-lived and initiate antigen activity, mainly an inflammatory response.
Dharmendra Kashyap +8 more
openaire +3 more sources
Frontiers in Microbiology, 2021 Escherichia coli produces extracellular vesicles called outer membrane vesicles (OMVs) by releasing a part of its outer membrane. We previously reported that the combined deletion of nlpI and mlaE, related to envelope structure and phospholipid ...
Yoshihiro Ojima +7 more
doaj +1 more source
bioRxiv, 2020 There is a pressing need for a gonorrhea vaccine due to the high disease burden associated with gonococcal infections globally and the rapid evolution of antibiotic resistance in Neisseria gonorrhoeae (Ng).
I. Leduc +10 more
semanticscholar +1 more source
Heliyon, 2019 Background: Gram-negative bacteria actively secrete outer membrane vesicles into the surrounding environment and these vesicles have been shown to play various physiological and protective roles such as carrying antibiotic-degrading enzymes and acting as
Wouter André van der Westhuizen +3 more
doaj +1 more source
Knockout of mlaA increases Escherichia coli virulence in a silkworm infection model.
PLoS ONE, 2022 The mlaA gene encodes a lipoprotein to maintain an outer membrane lipid asymmetry in gram-negative bacteria. Although the role of mlaA in bacterial virulence has been studied in several bacterial species, there are no reports of its role in E.
Haruka Nasu +3 more
doaj +2 more sources
Porphyromonas gingivalis Outer Membrane Vesicles Increase Vascular Permeability [PDF]
Journal of Dental Research, 2020 Periodontitis is increasingly associated with increased risk of cardiovascular and other systemic diseases. The Gram-negative anaerobe, Porphyromonas gingivalis, is a key periodontal pathogen, and several lines of evidence link the presence of this bacterium in the circulation with vascular disease.
Farrugia, C. +2 more
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Microbial biosynthesis of designer outer membrane vesicles [PDF]
Current Opinion in Biotechnology, 2014 Outer membrane vesicles (OMVs) are nanoscale proteoliposomes that are ubiquitously secreted by Gram-negative bacteria. Interest in these bioparticles has escalated over the years, leading to discoveries regarding their composition, production, and vaccine potential.
Jenny L, Baker +4 more
openaire +2 more sources