Results 61 to 70 of about 131,361 (186)

Proteomics of Aggregatibacter actinomycetemcomitans Outer Membrane Vesicles

PLOS ONE, 2015
Aggregatibacter actinomycetemcomitans is an oral and systemic pathogen associated with aggressive forms of periodontitis and with endocarditis. Outer membrane vesicles (OMVs) released by this species have been demonstrated to deliver effector proteins such as cytolethal distending toxin (CDT) and leukotoxin (LtxA) into human host cells and to act as ...
Kieselbach, Thomas, Zijnge, Vincent, Granström, Elisabeth, Oscarsson, Jan   +3 more
openaire   +5 more sources

Bacterial outer membrane vesicle biogenesis: a new mechanism and its implications

Microbial Cell, 2016
Outer membrane vesicle (OMV) release by Gram-negative bacteria has been observed and studied for decades. First considered as a by-product of cell lysis, it soon became evident that OMVs are actively secreted from the outer membrane (OM) of Gram-negative
Sandro Roier, Franz G. Zingl, Fatih Cakar, Stefan Schild   +3 more
doaj   +1 more source

Dinoroseobacter shibae Outer Membrane Vesicles Are Enriched for the Chromosome Dimer Resolution Site dif

mSystems, 2021
Outer membrane vesicles (OMVs) are universally produced by prokaryotes and play important roles in symbiotic and pathogenic interactions. They often contain DNA, but a mechanism for its incorporation is lacking. Here, we show that Dinoroseobacter shibae,
Hui Wang, Nicole Beier, Christian Boedeker, Helena Sztajer, Petra Henke, Meina Neumann-Schaal, Johannes Mansky, Manfred Rohde, Jörg Overmann, Jörn Petersen, Frank Klawonn, Martin Kucklick, Susanne Engelmann, Jürgen Tomasch, Irene Wagner-Döbler   +14 more
doaj   +1 more source

Outer Membrane Vesicle Production Facilitates LPS Remodeling and Outer Membrane Maintenance in Salmonella during Environmental Transitions

mBio, 2016
The ability of Gram-negative bacteria to carefully modulate outer membrane (OM) composition is essential to their survival. However, the asymmetric and heterogeneous structure of the Gram-negative OM poses unique challenges to the cell’s successful ...
Katherine E. Bonnington, Meta J. Kuehn
doaj   +1 more source

Membrane Vesicles as Drug Delivery Systems: Source, Preparation, Modification, Drug Loading, In Vivo Administration and Biodistribution, and Application in Various Diseases

Pharmaceutics, 2023
Bioinspired (or biologically inspired) drug delivery systems (DDSs) have been intensively studied in the last decades. As bioinspired DDSs, membrane vesicles, including extracellular vesicles (EVs) released from eukaryotic cells, outer membrane vesicles (
Chenhan Sun, Ying Qin, Hongda Zhuang, Yuan Zhang, Zhiwen Wu, Yong Chen   +5 more
doaj   +1 more source

Structure formation in binary mixtures of lipids and detergents: Self-assembly and vesicle division

, 2012
Self-assembly dynamics in binary surfactant mixtures and structure changes of lipid vesicles induced by detergent solution are studied using coarse-grained molecular simulations.
Noguchi, Hiroshi
core   +1 more source

Early stages of retinal development depend on Sec13 function [PDF]

, 2013
Summary ER-to-Golgi transport of proteins destined for the extracellular space or intracellular compartments depends on the COPII vesicle coat and is constitutive in all translationally active cells.
Cavodeassi, Florencia, Feng, Yi, Schmidt, Katy, Stephens, David J   +3 more
core   +3 more sources

The density of Braun's Lipoprotein determines vesicle production in E. coli.

PLoS ONE
Production of extracellular vesicles by Gram-negative bacteria is known to be associated with blebbing of the outer membrane. Several proteins within Gram-negative bacteria crosslink the outer membrane to the cell wall, and thereby stabilize the cell ...
Brian P Weaver, Fengjie Zhao, Yuanli Gao, James Q Boedicker, Christoph A Haselwandter   +4 more
doaj   +1 more source

Native silica nanoparticles are powerful membrane disruptors [PDF]

, 2015
Silica nanoparticles are under development for intracellular drug delivery applications but can also have cytotoxic effects including cell membrane damage.
Alkhammash, Hend I., Berthier, Rémy, de Planque, Maurits R.R., Li, Nan   +3 more
core   +1 more source

Charge-Reversal Instability in Mixed Bilayer Vesicles

, 2000
Bilayer vesicles form readily from mixtures of charged and neutral surfactants. When such a mixed vesicle binds an oppositely-charged object, its membrane partially demixes: the adhesion zone recruits more charged surfactants from the rest of the ...
A. D. Dinsmore, E. J. W. Vervey, H. Aranda-Espinosa, H. Totsuji, I. Rouzina, J. N. Israelachvili, J. Nardi, J. Nardi, J. Nardi, L. D. Landau, L. Guldbrand, L. Ramos, P. Attard, Philip Nelson, R. B. Gennis, R. Kjellander, R. Kjellander, R. Williams, S. A. Safran, S. H. Behrens, S. Hachisu, V. A. Parsegian, V. I. Perel, W. B. Russel, Yi Chen   +24 more
core   +2 more sources