Results 131 to 140 of about 162,214 (300)

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

Domain Growth, Budding, and Fission in Phase Separating Self-Assembled Fluid Bilayers

, 2005
A systematic investigation of the phase separation dynamics in self-assembled multi-component bilayer fluid vesicles and open membranes is presented. We use large-scale dissipative particle dynamics to explicitly account for solvent, thereby allowing for
Alberts B., Lipowsky R., Mohamed Laradji, P. B. Sunil Kumar, Yamamoto S.   +4 more
core   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Fusobacterium Nucleatum-Derived Outer Membrane Vesicles Promote Immunotherapy Resistance

International Dental Journal
Aim or purpose: To explore whether the F. nucleatum-derived outer membrane vesicles (F.n-OMVs) promote immune escape and malignant phenotype formation of HNSCC.
Li Weiping, Yan Ming, Chen Wantao, Ji Yikang, Wang Xiaoning, Dou Shengjin, Zhang Zhen, Wu Ruoyi, Mao Mengying   +8 more
doaj   +1 more source

Microglia Mitochondria Support Neuronal Maturation via Metabolic and Transcriptional Reprogramming in Human 3D In Vitro Brain Model

Advanced Science, EarlyView.
xx xx. ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contributors to ASD‐associated biology, yet the mechanisms linking these processes to neuronal development remain poorly defined ...
Sydney P. Sterben, Charitha C. Anamala, Sahan B. S. Kansakar, Vaishnavi Koduri, Volha Liaudanskaya   +4 more
wiley   +1 more source

Influence of Micro-mixing on the Size of Liposomes Self-Assembled from Miscible Liquid Phases

, 2013
Ethanol injection and variations of it are a class of methods where two miscible phases---one of which contains dissolved lipids---are mixed together leading to the self-assembly of lipid molecules to form liposomes. This method has been suggested, among
Phapal, Sopan, Sunthar, P
core   +2 more sources

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

Advanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang, Rucong Liu, Zibaguli Wubulikasimu, Wanqing Zhao, Jiaqi Huang, Jiaxuan Wang, Tianyuan Zhang, Rui Fan, Wei Kong, Qinghua Cui, Yang Li, Yuan Zhou   +11 more
wiley   +1 more source

Evaluation of the Effect of Outer Membrane Vesicles (EcN) as an Effective and New Postbiotic on Inhibiting the Growth of Staphylococcus Aureus [PDF]

Journal of Mazandaran University of Medical Sciences
Background and purpose: The use of antibiotics is one of the most important ways to deal with bacterial infections. However, the improper of antibiotics and the emergence of drug resistance have compromised the effectiveness of antibiotics ...
Tania MirHosseini, Ava Behrouzi, Sarvenaz Falsafi   +2 more
doaj  

Bacterial Outer Membrane Vesicles: From Physics to Clinical

MedComm – Biomaterials and Applications
Bacterial outer membrane vesicles (OMVs) are nanoscale vesicular structures naturally produced by Gram‐negative bacteria during growth. These vesicles encapsulate a diverse array of bioactive molecules, including proteins, nucleic acids, and ...
Jun Zhou, Shuang Zou, Derong Dai, Liqing He, Xingyu Mou, Ninglin Zhao, Hong Li, Rui Bao   +7 more
doaj   +1 more source

Bordetella Pertussis And Outer Membrane Vesicles

, 2022
Bordetella pertussis is the causative agent of a respiratory infection called pertussis (whooping cough) that can be fatal in newborns and infants. The pathogen produces a variety of antigenic compounds which alone or simultaneously can damage various host cells.
Colak, Cigdem Yilmaz, Tefon Ozturk, Burcu Emine   +1 more
openaire   +1 more source