Results 31 to 40 of about 36,915 (264)

The flaring drill in the Galactic centre

Astronomy & Astrophysics
Context. The mini-cavity is a low-density region observed in the complex of streams of ionized gas around the Galactic central supermassive black hole, Sgr A★, known as the mini-spiral.
Haas Jaroslav, Kroupa Pavel, Peißker Florian, Morris Mark R.   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Anisotropic Outflows and IGM Enrichment

, 2007

We have designed an analytical model for the evolution of anisotropic galactic outflows. These outflows follow the path of least resistance, and thus travel preferentially into low-density regions, away from cosmological structures where galaxies form.
M. Pieri, H. Martel, C. Grenon
core   +1 more source

H I envelope around the carbon star V420 Vul

Astronomy & Astrophysics
We report the detection of an extended 21-cm parsec-scale H I structure toward the Mira variable V420 Vul using archival Galactic Arecibo L-band Feed Array survey data.
Ouyang Xu-Jia, Zhang Yong, Zhang Chuan-Peng, Zhang Li-Yun   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Morphologies of protostellar outflows: an ALMA view [PDF]

, 2014
The formation of stars is usually accompanied by the launching of protostellar outflows. Observations with the Atacama Large Millimeter/sub-millimeter Array (ALMA) will soon revolutionize our understanding of the morphologies and kinematics of these ...
Seifried, D, Peters, T, Klaassen, P D, Banerjee, R, Klessen, R S   +4 more
core   +1 more source

A quantitative model for bipolar molecular outflows

, 2014
[[abstract]]Since their first discovery in 1980, nearly 200 bipolar molecular outflows have now been observed. These outflows appear to be a ubiquitous phenomenon in the star formation process, although their origin remains unclear.
Li, ZY;Shu, FH
core   +1 more source

Luminous red novae as shock-powered transients

Astronomy & Astrophysics
Luminous red novae (LRNe) are a class of optical transients resulting from the mergers of binary stars or common envelope events. The population displays heterogeneous light curves with extended luminosity plateaus and/or secondary peaks, suggested to be
Sneppen Albert, Hotokezaka Kenta, Irwin Christopher M.   +2 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

4U 1538–52 in a heartbeat

Astronomy & Astrophysics
Context. Galactic high-mass X-ray binaries (HMXBs) are important systems for studying accretion mechanisms onto compact objects and for investigating the complex stellar winds of massive stars.
Diez C. M., Dupourqué S., Doherty A.-L., Dickson D., Zainab A., Martínez-Núñez S., Torrejón J. M., Guillot S., Rouco Escorial A., Fürst F., Kretschmar P.   +10 more
doaj   +1 more source