Results 41 to 50 of about 36,915 (264)

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Ionised outflows in z similar to 2.4 quasar host galaxies [PDF]

open access: yes, 2015
Aims. Outflows driven by active galactic nuclei (AGN) are invoked by galaxy evolutionary models to quench star formation and to explain the origin of the relations observed locally between super-massive black holes and their host galaxies. We here aim to
A. Marconi   +81 more
core   +1 more source

Net Foreign Direct Investment Development Path of the EU Member States

open access: yesEkonomski Vjesnik, 2013
The main objective of this research was to investigate the relationship between net foreign direct investment outflow and economic development on a sample of the European Union (EU) Member States and the Republic of Croatia which is soon to become a full
Sanja Franc
doaj  

Dense Molecular Environments of B[e] Supergiants and Yellow Hypergiants

open access: yesGalaxies, 2023
Massive stars expel large amounts of mass during their late evolutionary phases. We aim to unveil the physical conditions within the warm molecular environments of B[e] supergiants (B[e]SGs) and yellow hypergiants (YHGs), which are known to be embedded ...
Michaela Kraus   +4 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

About the nature of Mercer14 [PDF]

open access: yes, 2011
We used UK Infrared Telescope (UKIRT) near-infrared (NIR) broad-band JHK photometry, narrow band imaging of the 1-0S(1) molecular hydrogen emission line and mid-infrared Spitzer IRAC data to investigate the nature of the young cluster Mercer14 ...
G. Ioannidis   +3 more
core   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

TPHO: a time-dependent photoionisation model for AGN outflows

open access: yes, 2022
Outflows in active galactic nuclei (AGN) are considered a promising candidate for driving AGN feedback at large scales. However, without information on the density of these outflows, we cannot determine how much kinetic power they are imparting to the ...
Erin Kara   +5 more
core   +1 more source

Dusty Common Envelope Evolution

open access: yesGalaxies
We present the first hydrodynamical simulations of common envelope evolution that include the formation of dust and the effect of radiation pressure on dust grains.
Lionel Siess   +8 more
doaj   +1 more source

FDI FLOWS IN EU COUNTRIES – TRACKING THE PANDEMIC CRISIS [PDF]

open access: yesAnnals of the University of Craiova: Economic Sciences Series, 2021
The global economy is trying to recover after the severe crisis caused by the COVID-19 pandemic and the immediate impact on foreign direct investments (FDI) is still serious.
Laura Vasilescu, Raducu Stefan Bratu
doaj  

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