Results 71 to 80 of about 12,045 (194)

P-1877. Daptomycin-Induced Creatine Phosphokinase Elevations Among Patients Requiring Outpatient Parenteral Antimicrobial Therapy

Open Forum Infectious Diseases
Background Daptomycin, a lipopeptide with broad-spectrum gram-positive activity, requires once-daily dosing with weekly creatine phosphokinase (CPK) monitoring for daptomycin-induced muscle injury.
Deanna M Berg, Amanda Binkley, Christina Maguire, A. Norris, Vasilios Athans   +4 more
semanticscholar   +1 more source

The OPAT opportunity for beta-lactam individualization

Antimicrobial Stewardship & Healthcare Epidemiology
Beta-lactam therapeutic drug monitoring has been growing in prevalence in the acute care hospital setting. Expansion of its use to outpatient parenteral antimicrobial therapy requires careful consideration of potential logistical and therapeutic barriers.
Lindsey M. Childs-Kean, Christina G. Rivera, Veena Venugopalan, Madelyn J. Johnson, Erin F. Barreto   +4 more
doaj   +1 more source

Evaluating the Educational Value of Artificial Intelligence in Pharmacotherapy Education

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Final‐year medical students frequently make prescribing errors, partly because they have had insufficient training in therapeutic reasoning. Students need to understand the underlying rationale behind a drug choice in order to subsequently apply that knowledge critically and independently.
Mariëlle G. Hartjes, Michiel J. Bakkum, Milan C. Richir, Michiel A. van Agtmael, Jelle Tichelaar   +4 more
wiley   +1 more source

Home‐Based Versus In‐Hospital Care in Pediatrics: A Systematic Review of Cost‐Effectiveness Studies

World Medical &Health Policy, Volume 18, Issue 2, June 2026.
ABSTRACT Home‐based care has emerged as a potential alternative to traditional hospital‐based care for children and adolescents worldwide. This systematic review aimed to systematically gather and critically assess the available evidence on the cost‐effectiveness of home‐based versus in‐hospital care for pediatric populations globally.
Luís Carlos Lopes‐Júnior, Raphael Manhães Pessanha, Wesley Rocha Grippa, Jonathan Grassi, Luiz Cláudio Barreto Silva Neto, Mariana Rabello Laignier, María Liliana Vásquez Ponce, Karla Anacleto de Vasconcelos, Regina Aparecida Garcia de Lima   +8 more
wiley   +1 more source

Paediatric Central Venous Access Devices: An Evidence and Gap Map of Global Research

Journal of Paediatrics and Child Health, Volume 62, Issue 5, Page 697-710, May 2026.
ABSTRACT Context Central venous access devices (CVADs) are essential in paediatric care but pose significant risks. Synthesising existing evidence is needed to guide safe, effective, and equitable practice amid evolving interventions and complex management needs.
Tricia M. Kleidon, Sabrina de Souza, Patrícia Kuerten Rocha, Elouise Comber, Jacqueline Cunninghame, Areum Hyun, Jefferson Wildes da Silva Moura, Amanda J. Ullman, Mari Takashima   +8 more
wiley   +1 more source

Effectiveness, Tolerance, and Safety of Meropenem in a Pediatric Outpatient Parenteral Antimicrobial Therapy Program. [PDF]

Can J Hosp Pharm
Yu S, Tremblay S, Coïc L, Bérard C, Martineau-Cyr PA, Forest JM, Chagnon J, Ovetchkine P, Tapiéro B.   +8 more
europepmc   +2 more sources

Exploring Affordable Curative Therapy for Sickle Cell Disease in Africa: A Comprehensive Overview

American Journal of Hematology, Volume 101, Issue S1, Page 56-74, April 2026.
ABSTRACT The practical aspects of developing curative treatments for sickle cell disease (SCD) in Africa, such as gene therapy and hematopoietic stem cell transplantation, involve strengthening healthcare infrastructure, training healthcare professionals, establishing regional treatment centers, and creating national SCD programs.
Adetola A. Kassim, Alexis A. Thompson, Punam Malik   +2 more
wiley   +1 more source

Evaluate the Effectiveness of Outpatient Parenteral Antimicrobial Therapy (OPAT) Program in Saudi Arabia: A Retrospective Study

, 2022
(1) Background: Outpatient parenteral antibiotic therapy (OPAT) is a well-established and cost-effective measure that improves the efficient use of healthcare resources and increases bed availability.
Abdul Haseeb, Ahmed Aljabri, Adnan Al Harbi, Mohammed A. Al-Ghanmi, Majed Ahmed Algarni, Haneen J. Al Shareef, Yasser Alatawi, Attiah Khobrani, Mohammed S. Alzahrani, Mahmoud E. Elrggal, Faisal AlSenani   +10 more
core   +1 more source

Identifying the potential impact of a multidisciplinary outpatient antimicrobial therapy program in an area of high social vulnerability

Therapeutic Advances in Infectious Disease, 2023
Background: Outpatient parenteral antimicrobial therapy (OPAT) and complex outpatient antimicrobial therapy (COpAT) are common practice in the management of infectious diseases (IDs). However, providing OPAT/COpAT can pose significant challenges pre- and
Karen K. Tan, Garret Hino, Anna Y. Zhou, Hadeel Al-Fayiz, Sasha Rodriguez, Jacinda C. Abdul-Mutakabbir   +5 more
doaj   +1 more source

Comprehensive Management of Diabetic Foot Ulcers: Current Evidence and Practice

Journal of Diabetes, Volume 18, Issue 4, April 2026.
This figure illustrates a multidisciplinary approach to the management of diabetic foot ulcers, including wound care, metabolic management, infection control, vascular intervention, and surgical treatment. Integration of these components is essential for optimizing healing, preventing complications, and preserving the limb.
Ji Min Kim, Seon Mee Kang, Jung Hwa Jung, Ki Chun Kim, Sanghyun Ahn, Chong Hwa Kim, Tae Sun Park, Ie Byung Park   +7 more
wiley   +1 more source