Results 51 to 60 of about 12,045 (194)

Experience with liposomal amphotericin B in outpatient parenteral antimicrobial therapy

, 2021
Outpatient parenteral antimicrobial therapy (OPAT) is a safe, effective, and convenient treatment strategy for patients receiving intravenous antimicrobials in the outpatient setting; however, data are limited describing the use and safety of liposomal ...
Hamad, Yasir, Powderly, William G., Spec, Andrej, Ahmed, Mohamed M, Burnett, Yvonne J., Ahmed, Mohamed M., Burnett, Yvonne J, Powderly, William G   +7 more
core   +1 more source

Risk of Treatment Failure in Outpatient Parenteral Antimicrobial Therapy From an Academic Medical Center in Kentucky. [PDF]

Open Forum Infect Dis
Background Outpatient parenteral antimicrobial therapy (OPAT) has many benefits, yet factors contributing to treatment failure are not well understood. This study aimed to identify risk factors for OPAT failure by comparing successful patients to those ...
Worsham Behal K, Stoner BJ, Schadler A, Burgess D, Burgess DS, Mynatt RP.   +5 more
europepmc   +2 more sources

Ampicillin Stability in a Portable Elastomeric Infusion Pump: A Step Forward in Outpatient Parenteral Antimicrobial Therapy

Pharmaceutics, 2023
Outpatient parenteral antimicrobial therapy (OPAT) with continuous infusion pumps is postulated as a very promising solution to treat complicated infections, such as endocarditis or osteomyelitis, that require patients to stay in hospital during extended
Lorena Rodríguez-Martínez, Ana Castro-Balado, Gonzalo Hermelo-Vidal, Enrique Bandín-Vilar, Iria Varela-Rey, Francisco José Toja-Camba, Teresa Rodríguez-Jato, Ignacio Novo-Veleiro, Pablo Manuel Varela-García, Irene Zarra-Ferro, Miguel González-Barcia, Cristina Mondelo-García, Jesús Mateos, Anxo Fernández-Ferreiro   +13 more
doaj   +1 more source

Hospital at Home in 10 years—Here, borrow my binoculars

Journal of Internal Medicine, EarlyView.
Abstract Hospital in the Home (HAH) refers to the delivery of acute hospital care to patients at home, or in their usual place of care, including nursing homes. HAH is an acute hospital substitution service—it delivers medical, nursing and allied health staff, skills, interventions and treatments, technologies and supervision usually found in hospitals
Michael Montalto
wiley   +1 more source

Clinical benefit of faecal microbiota transplantation administered via a single retention enema as an adjunctive treatment in dogs with chronic enteropathy: a randomised controlled trial

Journal of Small Animal Practice, EarlyView.
Objectives To evaluate the clinical benefit of faecal microbiota transplantation administered via a single retention enema, as an adjunctive treatment in the management of dogs with chronic enteropathy. Materials and Methods Blinded, randomised controlled trial.
F. Allerton, M. J. Whittle, L. Durkin, C. Prior, M. Trehy, H. Swales, F. Duplan, S. Borgonovi, G. Pinchbeck, I. Gajanayake, M. Dunning, T. Sparks, P. Watson, G. C. A. Amos, K. McCallum, J. Bazelle, A. Kent   +16 more
wiley   +1 more source

Tissue and Serum Concentrations of Time‐Dependent Antibiotics in Infected Diabetic Foot Ulcers by Bolus or Continuous Administration: The Randomised DFIATIM Trial

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 5, July 2026.
ABSTRACT Aims The clinical effectiveness of antibiotic (ATB) therapy in patients with infected diabetic foot ulcers (iDFUs) depends on achieving sufficient ATB concentrations in both serum and peripheral tissues. This study evaluated the availability and bactericidal activity of the time‐dependent ATBs—ceftazidime (CTZ) and amoxicillin/clavulanate (AMC)
Radka Jarošíková, Dominika Sojáková, Simona Antalová, Petr Tůma, Jan Polák, Michal Dubský, Andrea Němcová, Veronika Wosková, Pavol Beca, Istvan Modos, Jan Mareš, Jakub Mrázek, Chahrazed Mekadim, Markéta Skružná, Vladimíra Fejfarová   +14 more
wiley   +1 more source

Successful outpatient parenteral antimicrobial therapy with rezafungin for chronic pulmonary aspergillosis: a case report and health economic assessment. [PDF]

JAC Antimicrob Resist
Background Chronic pulmonary aspergillosis (CPA) is a serious lung disorder caused by Aspergillus fungal infection with high morbidity and mortality. Treatment options include antifungal azoles, polyenes and echinocandins.
Law SM, Choyce A, Barzinji H, Ellis H, Kosmidis C, Seaton RA.   +5 more
europepmc   +2 more sources

Sustained Treatment Success With Ustekinumab in Symptomatic Stricturing Crohn's Disease: A Retrospective Single‐Arm Observational Cohort Study

MedComm, Volume 7, Issue 7, July 2026.
Data on ustekinumab (UST) for symptomatic stricturing Crohn's disease remain scarce in China. This cohort study screened 73 patients from June 2022 to April 2024, of whom 54 were eligible included, with 81.5% achieving 52‐week treatment success. Most attained sustained clinical remission alongside improved inflammation and strictures. Nonsmoking status
Jingwen Liu, Wen Hu, Shuyan Li, Shurong Hu, Deming Jiang, Yan Chen   +5 more
wiley   +1 more source

Palliative outpatient parenteral antimicrobial therapy (OPAT): A single center experience and systematic scoping review

Clinical Infection in Practice, 2022
Traditionally, outpatient parenteral antimicrobial therapy (OPAT) is used to treat infections with predictable course and anticipated response to therapy. However, there has been little consideration of OPAT for palliation as opposed to cure.
Oyewole Chris Durojaiye, Ihsan Jibril, Evangelos I Kritsotakis   +2 more
doaj   +1 more source

Development and Physicochemical Stability of an Oral GS‐441524 Suspension for Weight‐Adjusted Treatment of Feline Infectious Peritonitis

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
A 50 mg/mL oral GS‑441524 suspension for feline infectious peritonitis (FIP) was developed and shown to remain physico‐chemically stable for at least 12 weeks under tested storage conditions and 28 days in‑use, supporting accurate weight‑adjusted dosing as an extemporaneously compounded formulation under veterinary supervision.
Cédric Wernli, Ursula Streit
wiley   +1 more source