Results 61 to 70 of about 5,466 (169)

The use, appropriateness and outcomes of outpatient parenteral antimicrobial therapy [PDF]

Archives of Disease in Childhood, 2016
ObjectiveOutpatient parenteral antimicrobial therapy (OPAT) is increasingly used to treat children at home, but studies in children are scarce. We aimed to describe the use, appropriateness and outcomes of OPAT in children.DesignThis was a 12-month prospective observational study.SettingThe hospital-in-the-home programme of The Royal Children's ...
Kate A Hodgson, Julie Huynh, Laila F Ibrahim, Bronwyn Sacks, Daniel Golshevsky, Michael Layley, Mark Spagnolo, Chin-Mae Raymundo, Penelope A Bryant   +8 more
openaire   +2 more sources

Evaluating the Educational Value of Artificial Intelligence in Pharmacotherapy Education

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Final‐year medical students frequently make prescribing errors, partly because they have had insufficient training in therapeutic reasoning. Students need to understand the underlying rationale behind a drug choice in order to subsequently apply that knowledge critically and independently.
Mariëlle G. Hartjes, Michiel J. Bakkum, Milan C. Richir, Michiel A. van Agtmael, Jelle Tichelaar   +4 more
wiley   +1 more source

Home‐Based Versus In‐Hospital Care in Pediatrics: A Systematic Review of Cost‐Effectiveness Studies

World Medical &Health Policy, Volume 18, Issue 2, June 2026.
ABSTRACT Home‐based care has emerged as a potential alternative to traditional hospital‐based care for children and adolescents worldwide. This systematic review aimed to systematically gather and critically assess the available evidence on the cost‐effectiveness of home‐based versus in‐hospital care for pediatric populations globally.
Luís Carlos Lopes‐Júnior, Raphael Manhães Pessanha, Wesley Rocha Grippa, Jonathan Grassi, Luiz Cláudio Barreto Silva Neto, Mariana Rabello Laignier, María Liliana Vásquez Ponce, Karla Anacleto de Vasconcelos, Regina Aparecida Garcia de Lima   +8 more
wiley   +1 more source

Paediatric Central Venous Access Devices: An Evidence and Gap Map of Global Research

Journal of Paediatrics and Child Health, Volume 62, Issue 5, Page 697-710, May 2026.
ABSTRACT Context Central venous access devices (CVADs) are essential in paediatric care but pose significant risks. Synthesising existing evidence is needed to guide safe, effective, and equitable practice amid evolving interventions and complex management needs.
Tricia M. Kleidon, Sabrina de Souza, Patrícia Kuerten Rocha, Elouise Comber, Jacqueline Cunninghame, Areum Hyun, Jefferson Wildes da Silva Moura, Amanda J. Ullman, Mari Takashima   +8 more
wiley   +1 more source

Exploring Affordable Curative Therapy for Sickle Cell Disease in Africa: A Comprehensive Overview

American Journal of Hematology, Volume 101, Issue S1, Page 56-74, April 2026.
ABSTRACT The practical aspects of developing curative treatments for sickle cell disease (SCD) in Africa, such as gene therapy and hematopoietic stem cell transplantation, involve strengthening healthcare infrastructure, training healthcare professionals, establishing regional treatment centers, and creating national SCD programs.
Adetola A. Kassim, Alexis A. Thompson, Punam Malik   +2 more
wiley   +1 more source

Comprehensive Management of Diabetic Foot Ulcers: Current Evidence and Practice

Journal of Diabetes, Volume 18, Issue 4, April 2026.
This figure illustrates a multidisciplinary approach to the management of diabetic foot ulcers, including wound care, metabolic management, infection control, vascular intervention, and surgical treatment. Integration of these components is essential for optimizing healing, preventing complications, and preserving the limb.
Ji Min Kim, Seon Mee Kang, Jung Hwa Jung, Ki Chun Kim, Sanghyun Ahn, Chong Hwa Kim, Tae Sun Park, Ie Byung Park   +7 more
wiley   +1 more source

Operational and data-integrity limitations of a system-wide Epic OPAT order set: a three-year cohort analysis

Antimicrobial Stewardship & Healthcare Epidemiology
We evaluated an Epic-based outpatient parenteral antimicrobial therapy (OPAT) order set to assess its impact on clinical workflows and analytics. Free text, missing structured fields, and lack of microbiology linkage made it difficult to track care ...
M. Yasser Alsafadi, Shivani Patel, Natalie Finch, Shemual Tsai, Wesley Hoffmann   +4 more
doaj   +1 more source

The Impact of a Structured Outpatient Parenteral Antimicrobial Therapy (OPAT) Programme on Quality of Care, Optimisation of Antimicrobial Use, and Healthcare Costs: A Retrospective Cohort Study

Antibiotics
Background/Objectives: In 2022, Spaarne Gasthuis hospital implemented an outpatient parenteral antimicrobial therapy (OPAT) programme, including mandatory infectious disease (ID) specialist assessment and integrated structured workflow, aiming to improve
Irene G. Manders, Darya Comello, Dennis Souverein, Sjoerd Euser, Bjorn L. Herpers, Judith Vetten, Jayant S. Kalpoe, Marco Goeijenbier, Steven F. L. van Lelyveld   +8 more
doaj   +1 more source

Role of outpatient parenteral antibiotic therapy in the treatment of community acquired skin and soft tissue infections in Singapore

BMC Infectious Diseases, 2017
Background Treatment of community acquired skin and soft tissue infections (SSTIs) is a common indication for outpatient parenteral antibiotic therapy (OPAT) in USA, UK and Australasia, however data from Asia are lacking.
Monica Chan, Chee Kheong Ooi, Joshua Wong, Lihua Zhong, David Lye   +4 more
doaj   +1 more source

Outpatient parenteral antimicrobial therapy with carbapenems: A systematic review

Journal of Infection
To review the literature on parenteral carbapenems in OPAT and present comprehensive evidence on their safety, efficacy, and stability.A systematic review following PRISMA guidelines was conducted through 17 January 2024, using PubMed, Embase, Web of Science, Scopus, and the Cochrane Library to find relevant articles.Ertapenem (1 g QD) in OPAT showed ...
Wolie, Z. T., Roberts, J. A., Wale, Y. M., Unwin, S., McCarthy, K., Sime, F. B.   +5 more
openaire   +4 more sources