Results 41 to 50 of about 239 (129)

Cost‐Effectiveness of Once Weekly Rezafungin for the Treatment of Invasive Candidiasis in the United Kingdom

Mycoses, Volume 69, Issue 2, February 2026.
ABSTRACT Background Invasive candidiasis (IC), life‐threatening fungal infections with high economic burden, are often treated first‐line with daily intravenous echinocandins. A new once weekly echinocandin, rezafungin, demonstrated statistically non‐inferior efficacy and numerically shorter intensive care unit (ICU) stay compared to caspofungin in ...
Noemi Muszbek, Alisha Angdembe, Carolina Garcia‐Vidal, Inga Bielicka, Keith R. Abrams, Keith Tolley, Markus Ruhnke, Maximilian Lebmeier, Neil Hawkins, Nick Manamley, Sara Dickerson   +10 more
wiley   +1 more source

Paediatric Outpatient Parenteral Antimicrobial Therapy (OPAT): An e-survey of the experiences of parents and clinicians.

PLoS ONE, 2021
BackgroundLittle evidence exists about parental satisfaction and their influence on referral to paediatric Outpatient Parenteral Antimicrobial Therapy (OPAT).AimThis study aimed to examine the experiences of parents, children and clinicians of OPAT at a ...
Bernie Carter, Debra Fisher-Smith, David Porter, Steven Lane, Matthew Peak, David Taylor-Robinson, Louise Bracken, Enitan D Carrol   +7 more
doaj   +1 more source

Rezafungin for Salvage or Consolidation Therapy of Invasive Fungal Disease: Experience in Real‐World Clinical Practice

Mycoses, Volume 69, Issue 2, February 2026.
ABSTRACT Background Echinocandins are the first‐line treatment for invasive candidiasis. Rezafungin is a novel echinocandin with improved pharmacokinetic properties that allow for once‐weekly intravenous administration, offering potential advantages in complex clinical settings.
Jorge Boán, Eduardo Aparicio‐Minguijón, Mario Fernández‐Ruiz, María Asunción Pérez‐Jacoiste Asín, Isabel Rodríguez‐Goncer, Francisco López‐Medrano, Rafael San‐Juan, José Tiago Silva, Ana Pérez‐Ayala, Jose Manuel Caro‐Teller, José María Aguado   +10 more
wiley   +1 more source

Operational and data-integrity limitations of a system-wide Epic OPAT order set: a three-year cohort analysis

Antimicrobial Stewardship & Healthcare Epidemiology
We evaluated an Epic-based outpatient parenteral antimicrobial therapy (OPAT) order set to assess its impact on clinical workflows and analytics. Free text, missing structured fields, and lack of microbiology linkage made it difficult to track care ...
M. Yasser Alsafadi, Shivani Patel, Natalie Finch, Shemual Tsai, Wesley Hoffmann   +4 more
doaj   +1 more source

Review of the first comprehensive outpatient parenteral antimicrobial therapy program in a tertiary care hospital in Japan

International Journal of Infectious Diseases, 2020
Objectives: The infectious diseases team at Kameda Medical Center, Japan, implemented a new outpatient parenteral antimicrobial therapy (OPAT) program in July 2012 and expanded the program with the support of home care services.
Ryota Hase, Yoshiaki Yokoyama, Hiroyuki Suzuki, Shunsuke Uno, Takahiro Mikawa, Daisuke Suzuki, Kiyoharu Muranaka, Naoto Hosokawa   +7 more
doaj   +1 more source

Evaluating Outpatient Parenteral Antimicrobial Therapy (OPAT) Clinic for Pediatric Infectious Conditions: Insights From Alberta Children’s Hospital

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Background The Outpatient Parenteral Antimicrobial Therapy (OPAT) Clinic at the Alberta Children’s Hospital (ACH) offers a vital service, enabling stable pediatric patients to receive intravenous (IV) antimicrobial therapy on an outpatient basis.
Danah Alsharrah, Tajdin Jadavji, Mariam Arabi   +2 more
wiley   +1 more source

Implementation of outpatient parenteral antimicrobial therapy program in the contemporary health care system: A narrative review of the evidence

Journal of Infection and Public Health
Outpatient parenteral antimicrobial therapy (OPAT) program has become an established clinical practice globally, though its implementation varies across jurisdictions. This review explores the implementation of OPAT within contemporary healthcare systems.
Solomon Ahmed Mohammed, Natasha Roberts, David Nicolás, Sean Unwin, Menino Cotta, Jason A. Roberts, Fekade B. Sime   +6 more
doaj   +1 more source

Safety and feasibility of outpatient parenteral antimicrobial therapy for patients with spinal infection

Scientific Reports, 2023
Outpatient parenteral antimicrobial therapy (OPAT) is a cost-effective method of administering intravenous antimicrobial therapy. Although OPAT is well established in the UK and US healthcare systems, few centres in Europe perform it.
Fatma Kilinc, Matthias Setzer, Bedjan Behmanesh, Daniel Jussen, Florian Gessler, Fee Keil, Volkhard A. J. Kempf, Johanna Kessel, Marcus Czabanka, Vincent Prinz   +9 more
doaj   +1 more source

Evaluate the Effectiveness of Outpatient Parenteral Antimicrobial Therapy (OPAT) Program in Saudi Arabia: A Retrospective Study

Antibiotics, 2022
(1) Background: Outpatient parenteral antibiotic therapy (OPAT) is a well-established and cost-effective measure that improves the efficient use of healthcare resources and increases bed availability.
Haneen J. Al Shareef, Adnan Al Harbi, Yasser Alatawi, Ahmed Aljabri, Mohammed A. Al-Ghanmi, Mohammed S. Alzahrani, Majed Ahmed Algarni, Attiah Khobrani, Abdul Haseeb, Faisal AlSenani, Mahmoud E. Elrggal   +10 more
doaj   +1 more source

Zoonotic Streptococcus canis Bacteremia Following a Dog Scratch in an Elderly Patient With a Nonconditional Pacemaker

Case Reports in Infectious Diseases, Volume 2026, Issue 1, 2026.
Streptococcus canis is a β‐hemolytic Group G streptococcus commonly found in the microbiome of dogs and cats and is an uncommon cause of invasive human infection. Although typically regarded as a veterinary pathogen, S. canis has been reported to cause bacteremia, endocarditis, and other severe infections in humans, particularly in older adults with ...
Kamel Alachraf, Patrick Trouten, Jessica Thayer, Larry M. Bush   +3 more
wiley   +1 more source