Results 61 to 70 of about 1,647 (162)

Evolving antimicrobial resistance in a patient receiving palliative OPAT for a vascular graft infection: A case report

Clinical Infection in Practice, 2019
Prosthetic vascular graft infection is devastating and frequently fatal. Cure requires removal of the graft and reperfusion by placement of a new graft. However, no evidence based guidelines exist for management where removal of the graft is not possible.
James W.D. Irvine, Ann L.N. Chapman, Carlos Varon Lopez, Kerry Reid, Michelle Spittal, Steven McCormick, Stephanie Dundas   +6 more
doaj   +1 more source

Qualitative analysis of barriers and facilitators to healthcare engagement for people with injecting‐related invasive infections using a social ecological framework

Addiction, Volume 120, Issue 12, Page 2476-2488, December 2025.
Abstract Background and aims Injecting‐related bacterial infections are increasing in many countries. Systemic infections often require prolonged treatment. Evidence suggests that people who inject drugs who have invasive infections are less likely to complete antimicrobial treatment and have poorer outcomes than patients without a history of injecting
Lucy O. Attwood, Sophia E. Schroeder, Olga Vujovic, Andrew J. Stewardson, Joseph S. Doyle, Paul Dietze, Peter Higgs, Samantha Colledge‐Frisby   +7 more
wiley   +1 more source

Successful Establishment of an Antimicrobial Stewardship Program (ASP) for Outpatient Parenteral Antimicrobial Therapy (OPAT) [PDF]

Open Forum Infectious Diseases, 2017
BACKGROUND: IDSA guidelines for implementing an ASP were published in 2016 with required standards by The Joint Commission for hospitals beginning January, 2017. To date, no guidelines have been established in the US for ASP specific to OPAT. Using current guidelines, along with those proposed for the UK, we developed an ASP program unique to OPAT ...
Nathan, Ramesh V, Adams, John S, Dretler, Robin H, Luu, Quyen, Metzger, Brian S, Schroeder, Claudia P, Couch, Kimberly, Van Anglen, Lucinda J   +7 more
openaire   +1 more source

Rezafungin Utilisation in Real Life—FungiScope Results From Europe and the United States

Mycoses, Volume 68, Issue 9, September 2025.
ABSTRACT Background Rezafungin, a novel echinocandin with once‐weekly intravenous dosing, offers potential advantages for outpatient parenteral antifungal therapy (OPAT) in invasive candidiasis (IC). While clinical trial data support its efficacy and safety, real‐world experience remains limited.
Ilana Reinhold, Giovanni Mori, Massimiliano Lanzafame, Alessandro Limongelli, Antonio Vena, Julia Götz, Stilla Bauernfeind, Frank Hanses, Lukas Tometten, Michael Mayer, Ansgar Rieke, Ana Soriano‐Martin, Maricela Valerio, Jose A. Vazquez, Patrick Yue, Laman Rahimli, Nijat Azimli, Ertan Sal, Jon Salmanton‐García, Natalia Vasenda, Rosanne Sprute, Jannik Stemler, Sebastian Wingen‐Heimann, Oliver A. Cornely, Danila Seidel   +24 more
wiley   +1 more source

Safety and Efficacy of Outpatient Parenteral Antibiotic Therapy (OPAT) in Patients With Infective Endocarditis: A Systematic Review and Meta‐Analysis

Clinical Cardiology, Volume 48, Issue 5, May 2025.
ABSTRACT Background Infective endocarditis (IE) is a life‐threatening infection requiring prolonged intravenous antimicrobial therapy. Outpatient parenteral antibiotic therapy (OPAT) has emerged as an alternative to prolonged hospitalization, but its safety and efficacy in IE remain debated.
Hamza Ashraf, Zain Ali Nadeem, Khawaja Abdul Rehman, Shanzay Akhtar, Haider Ashfaq, Muhammad Sohaib Khan, Mahad Butt, Ibrahim Nagmeldin, Eeshal Fatima, Muhammad Waqas, Aalaa Saleh, Hritvik Jain, Raheel Ahmed   +12 more
wiley   +1 more source

A bundle of the top 10 OPAT publications in 2024

Antimicrobial Stewardship & Healthcare Epidemiology
Objective: Outpatient parenteral antimicrobial therapy (OPAT) is a mainstay of clinical infectious diseases practice, and OPAT-related publications continue to be prominent in journals.
Lindsey M. Childs-Kean, Sara F. Azimi, Alison M. Beieler, Laila Castellino, Sara C. Keller, Margaret Pertzborn, Alexandra Yamshchikov, Leah H. Yoke, Kathleen Young, Monica V. Mahoney   +9 more
doaj   +1 more source

751Outpatient Parenteral Antimicrobial Therapy (OPAT) Outcomes at a Tertiary Care Hospital [PDF]

Open Forum Infectious Diseases, 2014
updated) Background: The practice of OPAT became widespread with demonstration of its safety in selected patients. However, with concerted efforts to reduce hospital lengths of stay, there is currently no selection for OPAT. Virtually every patient is a potential candidate for OPAT. Data on OPAT outcomes with unselected patients are very limited.
Shrestha, Nabin, Shrestha, Jugnu, Everett, Angela, Carroll, Don, Gordon, Steven, Rehm, Susan J.   +5 more
openaire   +1 more source

Complicated and deep bacterial skin and soft tissue infections

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 3, Page 357-375, March 2025.
Summary Complicated erysipelas, cellulitis, and necrotizing soft tissue infections belong to the spectrum of bacterial infections affecting the skin and underlying soft tissues. Their frequency as well as risk of recurrence and complicated disease course pose a significant health burden.
Christine Prodinger, Arno Lechner, Arno Hintersteininger, Jan Marco Kern, Matthias Meißnitzer, Damian Meyersburg, Johann W. Bauer, Martin Laimer   +7 more
wiley   +1 more source

An overview of Hospital‐at‐home versus other models of care

Journal of General and Family Medicine, Volume 26, Issue 1, Page 19-26, January 2025.
How Hospital‐at‐home contrasts to traditional inpatient models were outlined. How Hospital‐at‐home is implemented in an acute hospital setting were also being described. The Hospital‐at‐home model offers a compelling blueprint for what the future of acute care might look like. Abstract Despite being increasingly adopted in various regions, the model of
Hai Liang Marc Wong, Chong Yau Ong, Hui Juan Ngo, Si Sen Yeo, Mui Hua Jean Lee   +4 more
wiley   +1 more source

Outpatient Parenteral Antimicrobial Therapy in Pediatric Patients

Journal of Behçet Uz Children's Hospital
Objective: Outpatient parenteral antimicrobial therapy (OPAT) has been developed as an alternative approach to hospital stay for the effective treatment of infections requiring long-term therapy. The aim of this study is to evaluate the clinical outcomes
Hıncal Özbakır, Deniz Ergün, Pelin Kaçar, Berna Kahraman Çetin, Arife Özer, Çağla Özbakır, Gizem Güner Özenen, Aybüke Akaslan Kara, Dilek Orbatu, Nuri Bayram, İlker Devrim   +10 more
doaj   +1 more source